Journal article
Surface Engineered Nanoparticles: Considerations for Biomedical Applications
Advanced engineering materials, Vol.19(11), pp.1700302-n/a
11/2017
DOI: 10.1002/adem.201700302
Abstract
The development of reproducible methods for the fabrication of nanoparticles in the 21st century is a major scientific achievement. Currently, there are many well‐established methods for the production of nanoparticles of different shapes, sizes, and compositions. Along with these advancements in nanotechnology, nanoparticles have emerged as excellent tools for a diverse range of applications and have become a focus of research globally. With fundamental research being established, efforts are now being directed toward intelligently designed nanoparticles in which the properties of the nanomaterial are finely tuned depending on the application of interest. Usually, this involves the functionalization of the nanoparticle surface with a ligand. In this review, the impact of nanoparticle surface chemistry is discussed as it applies to biological systems.
This review summarizes the current approaches for modifying nanoparticle surfaces and the impact on biological systems. Contained in this writing is a wide variety of examples where ligands (such as drugs, polymers, or proteins) are used to tailor the properties of nanoparticles for various biologically‐related applications. These applications include targeted drug delivery, biomedical imaging, or the design of safer and more biocompatible nanomaterials.
Details
- Title: Subtitle
- Surface Engineered Nanoparticles: Considerations for Biomedical Applications
- Creators
- Angie S Morris - University of IowaAliasger K Salem - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Advanced engineering materials, Vol.19(11), pp.1700302-n/a
- DOI
- 10.1002/adem.201700302
- ISSN
- 1438-1656
- eISSN
- 1527-2648
- Number of pages
- 10
- Language
- English
- Date published
- 11/2017
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Pharmaceutical Sciences and Experimental Therapeutics; Craniofacial Anomalies Research Center; Dental Research; Chemical and Biochemical Engineering
- Record Identifier
- 9984217460202771
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