Journal article
Surface modification of biomedical and dental implants and the processes of inflammation, wound healing and bone formation
International journal of molecular sciences, Vol.11(1), pp.354-369
01/25/2010
DOI: 10.3390/ijms11010354
PMCID: PMC2821008
PMID: 20162020
Abstract
Bone adaptation or integration of an implant is characterized by a series of biological reactions that start with bone turnover at the interface (a process of localized necrosis), followed by rapid repair. The wound healing response is guided by a complex activation of macrophages leading to tissue turnover and new osteoblast differentiation on the implant surface. The complex role of implant surface topography and impact on healing response plays a role in biological criteria that can guide the design and development of future tissue-implant surface interfaces.
Details
- Title: Subtitle
- Surface modification of biomedical and dental implants and the processes of inflammation, wound healing and bone formation
- Creators
- Clark M Stanford - University of Iowa
- Resource Type
- Journal article
- Publication Details
- International journal of molecular sciences, Vol.11(1), pp.354-369
- DOI
- 10.3390/ijms11010354
- PMID
- 20162020
- PMCID
- PMC2821008
- NLM abbreviation
- Int J Mol Sci
- ISSN
- 1422-0067
- eISSN
- 1422-0067
- Grant note
- UL1 RR024979 / NCRR NIH HHS UL1RR024979 / NCRR NIH HHS
- Language
- English
- Date published
- 01/25/2010
- Academic Unit
- Roy J. Carver Department of Biomedical Engineering; Dentistry Administration; Prosthodontics; Orthopedics and Rehabilitation; Craniofacial Anomalies Research Center
- Record Identifier
- 9984367641002771
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