Journal article
Surfactant and neonatal hemodynamics during the postnatal transition
Seminars in fetal & neonatal medicine, Vol.28(6), 101498
12/2023
DOI: 10.1016/j.siny.2023.101498
PMID: 38040585
Abstract
Surfactant replacement therapy (SRT) has revolutionized the management of respiratory distress syndrome (RDS) in premature infants, leading to improved survival rates and decreased morbidity. SRT may, however, be associated with hemodynamic changes, which can have both positive and negative effects on the immature cardiovascular system, during the transitional adaptation from fetal to extrauterine environment. However, there is a relative paucity of evidence in this domain, with most of them derived from small heterogeneous observational studies providing conflicting results. In this review, we will discuss the hemodynamic changes that occur with surfactant administration during this vulnerable period, focusing on available evidence regarding changes in pulmonary and systemic blood flow, cerebral circulation and their clinical implications.
Details
- Title: Subtitle
- Surfactant and neonatal hemodynamics during the postnatal transition
- Creators
- Sanoj Km Ali - University of TasmaniaAmy H Stanford - University of IowaPatrick J McNamara - University of IowaSamir Gupta - Sidra Medical and Research Center
- Resource Type
- Journal article
- Publication Details
- Seminars in fetal & neonatal medicine, Vol.28(6), 101498
- DOI
- 10.1016/j.siny.2023.101498
- PMID
- 38040585
- eISSN
- 1878-0946
- Language
- English
- Electronic publication date
- 11/23/2023
- Date published
- 12/2023
- Academic Unit
- Stead Family Department of Pediatrics; Neonatology; Internal Medicine
- Record Identifier
- 9984520558802771
Metrics
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