Journal article
Surgeon-Performed Ultrasound for Preoperative Localization of Abnormal Parathyroid Glands in Patients with Primary Hyperparathyroidism
World journal of surgery, Vol.30(9), pp.1658-1663
09/2006
DOI: 10.1007/s00268-005-0660-2
PMID: 16855801
Abstract
The introduction of portable ultrasound equipment enables surgeons to perform ultrasound examinations in a clinic setting. This study was undertaken to evaluate surgeon-performed ultrasound (SP-US) in patients with primary hyperparathyroidism (PHPT).Between July 2003 and March 2004, 65 patients with PHPT were evaluated with SP-US and 48 of these patients underwent parathyroid surgery. Among this group of 48 evaluable patients, 47 had preoperative imaging with technetium-99m sestamibi scanning (MIBI), and 12 had an additional ultrasound examination at an external radiology department (RP-US).All patients were cured of PHPT and the operative findings were used to determine the true status of the parathyroid glands of each patient. Twenty-four (50%) patients had concomitant thyroid nodules which were identified by SP-US, and 4 (8.3%) patients had simultaneous thyroid operations, 2 of which were for thyroid cancer. Considering data for all patients, SP-US had significantly higher sensitivity than MIBI or RP-US (60% vs. 46%, P = 0.013, and 60% vs. 11%, P = 0.004 respectively). Among the patients with a single adenoma, SP-US, MIBI, and RP-US had sensitivities of 83%, 63%, and 13% respectively. The specificities of all three imaging techniques were uniformly high and were not significantly different from each other.Surgeon-performed ultrasound is an accurate modality for localizing abnormal parathyroid glands in patients with PHPT, with results that compare favorably with other parathyroid imaging modalities.
Details
- Title: Subtitle
- Surgeon-Performed Ultrasound for Preoperative Localization of Abnormal Parathyroid Glands in Patients with Primary Hyperparathyroidism
- Creators
- John Kairys - Department of Surgery Thomas Jefferson University Philadelphia PA USAConstantine Daskalakis - Department of Pharmacology and Experimental Therapeutics, Division of Biostatistics Thomas Jefferson University Philadelphia PA USARonald Weigel - Department of Surgery University of Iowa 200 Hawkins Drive, Room 1516 JCP Iowa City IA USA 52242-1086
- Resource Type
- Journal article
- Publication Details
- World journal of surgery, Vol.30(9), pp.1658-1663
- Publisher
- Springer-Verlag; New York
- DOI
- 10.1007/s00268-005-0660-2
- PMID
- 16855801
- ISSN
- 0364-2313
- eISSN
- 1432-2323
- Language
- English
- Date published
- 09/2006
- Academic Unit
- Molecular Physiology and Biophysics; Anatomy and Cell Biology; Surgery; Biochemistry and Molecular Biology
- Record Identifier
- 9984025267602771
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