Journal article
Surgical Predictors of Clinical Outcome 6 Years After Revision ACL Reconstruction
The American journal of sports medicine, Vol.52(13), 3286
11/01/2024
DOI: 10.1177/03635465241288227
PMCID: PMC11796288
PMID: 39503722
Abstract
Revision anterior cruciate ligament (ACL) reconstruction has been documented to have inferior outcomes compared with primary ACL reconstruction. The reasons why remain unknown.BACKGROUNDRevision anterior cruciate ligament (ACL) reconstruction has been documented to have inferior outcomes compared with primary ACL reconstruction. The reasons why remain unknown.To determine whether surgical factors performed at the time of revision ACL reconstruction can influence a patient's outcome at 6-year follow-up.PURPOSETo determine whether surgical factors performed at the time of revision ACL reconstruction can influence a patient's outcome at 6-year follow-up.Cohort study; Level of evidence, 2.STUDY DESIGNCohort study; Level of evidence, 2.Patients who underwent revision ACL reconstruction were identified and prospectively enrolled between 2006 and 2011. Data collected included baseline patient characteristics, surgical technique and pathology, and a series of validated patient-reported outcome instruments: Knee injury and Osteoarthritis Outcome Score (KOOS), International Knee Documentation Committee (IKDC) subjective form, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx activity rating score. Patients were followed up for 6 years and asked to complete the identical set of outcome instruments. Regression analysis was used to control for baseline patient characteristics and surgical variables to assess the surgical risk factors for clinical outcomes 6 years after surgery.METHODSPatients who underwent revision ACL reconstruction were identified and prospectively enrolled between 2006 and 2011. Data collected included baseline patient characteristics, surgical technique and pathology, and a series of validated patient-reported outcome instruments: Knee injury and Osteoarthritis Outcome Score (KOOS), International Knee Documentation Committee (IKDC) subjective form, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and Marx activity rating score. Patients were followed up for 6 years and asked to complete the identical set of outcome instruments. Regression analysis was used to control for baseline patient characteristics and surgical variables to assess the surgical risk factors for clinical outcomes 6 years after surgery.A total of 1234 patients were enrolled (716 men, 58%; median age, 26 years), and 6-year follow-up was obtained on 79% of patients (980/1234). Using an interference screw for femoral fixation compared with a cross-pin resulted in significantly better outcomes in 6-year IKDC scores (odds ratio [OR], 2.2; 95% CI, 1.2-3.9; P = .008) and KOOS sports/recreation and quality of life subscale scores (OR range, 2.2-2.7; 95% CI, 1.2-4.8; P < .01). Use of an interference screw compared with a cross-pin resulted in a 2.6 times less likely chance of having a subsequent surgery within 6 years. Use of an interference screw for tibial fixation compared with any combination of tibial fixation techniques resulted in significantly improved scores for IKDC (OR, 1.96; 95% CI, 1.3-2.9; P = .001); KOOS pain, activities of daily living, and sports/recreation subscales (OR range, 1.5-1.6; 95% CI, 1.0-2.4; P < .05); and WOMAC pain and activities of daily living subscales (OR range, 1.5-1.8; 95% CI, 1.0-2.7; P < .05). Use of a transtibial surgical approach compared with an anteromedial portal approach resulted in significantly improved KOOS pain and quality of life subscale scores at 6 years (OR, 1.5; 95% CI, 1.02-2.2; P≤ .04).RESULTSA total of 1234 patients were enrolled (716 men, 58%; median age, 26 years), and 6-year follow-up was obtained on 79% of patients (980/1234). Using an interference screw for femoral fixation compared with a cross-pin resulted in significantly better outcomes in 6-year IKDC scores (odds ratio [OR], 2.2; 95% CI, 1.2-3.9; P = .008) and KOOS sports/recreation and quality of life subscale scores (OR range, 2.2-2.7; 95% CI, 1.2-4.8; P < .01). Use of an interference screw compared with a cross-pin resulted in a 2.6 times less likely chance of having a subsequent surgery within 6 years. Use of an interference screw for tibial fixation compared with any combination of tibial fixation techniques resulted in significantly improved scores for IKDC (OR, 1.96; 95% CI, 1.3-2.9; P = .001); KOOS pain, activities of daily living, and sports/recreation subscales (OR range, 1.5-1.6; 95% CI, 1.0-2.4; P < .05); and WOMAC pain and activities of daily living subscales (OR range, 1.5-1.8; 95% CI, 1.0-2.7; P < .05). Use of a transtibial surgical approach compared with an anteromedial portal approach resulted in significantly improved KOOS pain and quality of life subscale scores at 6 years (OR, 1.5; 95% CI, 1.02-2.2; P≤ .04).There are surgical variables at the time of ACL revision that can modify clinical outcomes at 6 years. Opting for a transtibial surgical approach and choosing an interference screw for femoral and tibial fixation improved patients' odds of having a significantly better 6-year clinical outcome in this cohort.CONCLUSIONThere are surgical variables at the time of ACL revision that can modify clinical outcomes at 6 years. Opting for a transtibial surgical approach and choosing an interference screw for femoral and tibial fixation improved patients' odds of having a significantly better 6-year clinical outcome in this cohort.
Details
- Title: Subtitle
- Surgical Predictors of Clinical Outcome 6 Years After Revision ACL Reconstruction
- Creators
- Brian R Wolf - University of IowaRick W Wright - Vanderbilt UniversityLaura J Huston - Vanderbilt UniversityAmanda K Haas - Washington University in St. LouisJacquelyn S Pennings - Vanderbilt UniversityChristina R Allen - Yale UniversityDaniel E Cooper - Vanderbilt UniversityThomas M DeBerardino - The University of Texas Health Science Center at San AntonioWarren R Dunn - Texas Orthopedic HospitalBrett Brick A LantzKurt P Spindler - Cleveland ClinicMichael J Stuart - Mayo Clinic in ArizonaAnnunziato Ned Amendola - Duke UniversityChristopher C Annunziata - Vanderbilt UniversityRobert A Arciero - UConn HealthBernard R Bach - Rush University Medical CenterChamp L Baker - Hughston ClinicArthur R Bartolozzi - Vanderbilt UniversityKeith M Baumgarten - Orthopedic InstituteJeffrey H Berg - Vanderbilt UniversityGeoffrey A Bernas - Vanderbilt UniversityStephen F Brockmeier - University of VirginiaRobert H Brophy - Washington University in St. LouisCharles A Bush-Joseph - Vanderbilt UniversityJ Brad Butler - Oregon ClinicJames L Carey - University of PennsylvaniaJames E Carpenter - Vanderbilt UniversityBrian J Cole - Rush University Medical CenterJonathan M Cooper - HealthPartnersCharles L Cox - Vanderbilt UniversityR Alexander Creighton - University of North Carolina at Chapel HillTal S David - Vanderbilt UniversityDavid C Flanigan - The Ohio State UniversityRobert W Frederick - Thomas Jefferson UniversityTheodore J Ganley - Children's Hospital of PhiladelphiaCharles J Gatt - University Orthopaedic AssociatesSteven R Gecha - Vanderbilt UniversityJames Robert Giffin - Fowler Kennedy Sport Medicine ClinicSharon L Hame - University of California, Los AngelesJo A Hannafin - Hospital for Special SurgeryChristopher D Harner - The University of Texas Health Science Center at HoustonNorman Lindsay Harris - Vanderbilt UniversityKeith S Hechtman - Vanderbilt UniversityElliott B Hershman - Lenox Hill HospitalRudolf G Hoellrich - Vanderbilt UniversityDavid C Johnson - Vanderbilt UniversityTimothy S Johnson - Vanderbilt UniversityMorgan H Jones - Vanderbilt UniversityChristopher C Kaeding - The Ohio State UniversityGanesh V Kamath - University of North Carolina at Chapel HillThomas E Klootwyk - Vanderbilt UniversityBruce A Levy - Orlando HealthC Benjamin MaG Peter Maiers - Methodist Sports MedicineRobert G Marx - Hospital for Special SurgeryMatthew J Matava - Washington University in St. LouisGregory M Mathien - Tennessee Orthopaedic ClinicsDavid R McAllister - University of California, Los AngelesEric C McCarty - University of Colorado DenverRobert G McCormack - Fraser HealthBruce S Miller - University of MichiganCarl W Nissen - Connecticut Children's Medical CenterDaniel F O'NeillBrett D Owens - Brown UniversityRichard D Parker - Cleveland ClinicMark L Purnell - Vanderbilt UniversityArun J Ramappa - Beth Israel Deaconess Medical CenterMichael A Rauh - University at Buffalo, State University of New YorkArthur C Rettig - Methodist Sports MedicineJon K Sekiya - University of MichiganKevin G Shea - Stanford UniversityOrrin H Sherman - Vanderbilt UniversityJames R Slauterbeck - Southeastern HealthMatthew V Smith - Washington University in St. LouisJeffrey T Spang - University of North Carolina at Chapel HillSteven J Svoboda - Vanderbilt UniversityTimothy N Taft - University of North Carolina at Chapel HillJoachim J Tenuta - Albany Medical Center HospitalEdwin M Tingstad - Vanderbilt UniversityArmando F Vidal - Vanderbilt UniversityDarius G Viskontas - Fraser InstituteRichard A White - Fitzgibbon HospitalJames S Williams - Cleveland ClinicMichelle L Wolcott - University of Colorado Anschutz Medical CampusJames J York - Vanderbilt University
- Resource Type
- Journal article
- Publication Details
- The American journal of sports medicine, Vol.52(13), 3286
- DOI
- 10.1177/03635465241288227
- PMID
- 39503722
- PMCID
- PMC11796288
- NLM abbreviation
- Am J Sports Med
- ISSN
- 1552-3365
- eISSN
- 1552-3365
- Publisher
- SAGE PUBLICATIONS INC
- Language
- English
- Date published
- 11/01/2024
- Academic Unit
- Orthopedics and Rehabilitation; Physical Therapy and Rehabilitation Science
- Record Identifier
- 9984742559402771
Metrics
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