Journal article
Surgical site infections and their prevention
Current opinion in infectious diseases, Vol.25(4), pp.378-384
08/2012
DOI: 10.1097/QCO.0b013e32835532f7
PMID: 22691686
Abstract
Recent studies have assessed interventions and bundles of interventions to prevent surgical site infections (SSIs). We reviewed numerous studies to identify those with the strongest evidence supporting interventions for preventing SSIs.
Bundles that included more than one intervention to decrease the risk of Staphylococcus aureus wound contamination, such as chlorhexidine bathing and nasal application of mupirocin, had the strongest supporting evidence. However, bundles should be tested to ensure that their components are not antagonistic. Vancomycin prophylaxis and extended antimicrobial prophylaxis should not be used routinely, but should be reserved for high-risk populations such as patients who carry methicillin-resistant S. aureus (MRSA). Novel interventions to prevent SSIs (e.g., topical or oral antimicrobial agents, skin sealant, and antimicrobial sutures) need further evaluation before surgeons implement them routinely.
There is some evidence that bundled interventions can reduce SSIs. However, more research should be done evaluating the effectiveness of these interventions. Future studies of bundles should use robust methodologies, such as randomized controlled trials, cluster randomized trials, or quasi-experimental studies analyzed by time series analysis.
Details
- Title: Subtitle
- Surgical site infections and their prevention
- Creators
- Marin L Schweizer - Department of Internal Medicine, University of Iowa Carver College of Medicine, Iowa City, Iowa, USALoreen A Herwaldt
- Resource Type
- Journal article
- Publication Details
- Current opinion in infectious diseases, Vol.25(4), pp.378-384
- DOI
- 10.1097/QCO.0b013e32835532f7
- PMID
- 22691686
- ISSN
- 0951-7375
- eISSN
- 1473-6527
- Language
- English
- Date published
- 08/2012
- Academic Unit
- Infectious Diseases; Epidemiology; General Internal Medicine; Internal Medicine
- Record Identifier
- 9984094384802771
Metrics
24 Record Views