Survival and short-term respiratory outcomes of < 750 g infants initially intubated with 2.0 mm vs. 2.5 mm endotracheal tubes

Jennifer N. Berger; Timothy G. Elgin; John M. Dagle; Jonathan M. Klein; Tarah T. Colaizy

doi:10.1038/s41372-021-01227-y

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Survival and short-term respiratory outcomes of < 750 g infants initially intubated with 2.0 mm vs. 2.5 mm endotracheal tubes

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Survival and short-term respiratory outcomes of < 750 g infants initially intubated with 2.0 mm vs. 2.5 mm endotracheal tubes

Jennifer N. Berger, Timothy G. Elgin, John M. Dagle, Jonathan M. Klein and Tarah T. Colaizy

Journal of perinatology, Vol.42(2), pp.202-208

02/01/2022

DOI: 10.1038/s41372-021-01227-y

PMCID: PMC8529572

PMID: 34675371

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Abstract

Objectives To compare survival and short-term respiratory outcomes of infants weighing <750 g initially intubated with 2.0 mm versus 2.5 mm endotracheal tube (ETT). Study design Retrospective, observational cohort study. Results Of 149 inborn infants weighing <750 g admitted to the NICU, 69 (46%) were intubated with 2.0 mm ETT, 78 with 2.5 mm ETT (53%), and 2 infants never required intubation. Infants intubated with 2.0 mm ETT were more premature (median gestational age (GA) 23 weeks (22, 24) vs. 24 weeks (24, 25) p < 0.0001), smaller (median birth weight 545 g (450, 616) vs. 648 g (579, 700), p < 0.0001), and more frequently intubated at delivery (96% vs. 68%, p < 0.00001). Survival to discharge was similar 77%, 53/69 and 87%, 68/78 (p = 0.09). Adjusted for GA, there were no significant differences in ventilator days (p = 0.7338) or Grade 3 BPD. Conclusions Premature infants born at a median GA of 23 weeks and median birth weight of 545 g can be successfully managed with 2.0 mm ETT.

Life Sciences & Biomedicine

Obstetrics & Gynecology

Pediatrics

Science & Technology

Details

Title: Subtitle: Survival and short-term respiratory outcomes of < 750 g infants initially intubated with 2.0 mm vs. 2.5 mm endotracheal tubes
Creators: Jennifer N. Berger - Children's Minnesota, Neonatal Medicine, Minneapolis, MN, USA.
Timothy G. Elgin - University of Iowa
John M. Dagle - University of Iowa
Jonathan M. Klein - University of Iowa
Tarah T. Colaizy - University of Iowa
Resource Type: Journal article
Publication Details: Journal of perinatology, Vol.42(2), pp.202-208
DOI: 10.1038/s41372-021-01227-y
PMID: 34675371
PMCID: PMC8529572
NLM abbreviation: J Perinatol
ISSN: 0743-8346
eISSN: 1476-5543
Publisher: Springer Nature
Number of pages: 7
Grant note: University of Iowa
Language: English
Date published: 02/01/2022
Academic Unit: Stead Family Department of Pediatrics; Epidemiology; Biochemistry and Molecular Biology; Neonatology
Record Identifier: 9984293083602771

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