Journal article
Survival of the resilient: Mechano-adaptation of circulating tumor cells to fluid shear stress
Molecular & cellular oncology, Vol.7(4), pp.1766338-1766338
07/03/2020
DOI: 10.1080/23723556.2020.1766338
PMCID: PMC7469561
PMID: 32944626
Abstract
During metastasis, cancer cells traverse the circulation to reach distant organs. Conventionally, this journey has been regarded as mechanically destructive to circulating tumor cells from solid tissues. We have recently shown that cancer cells from diverse tissues actively resist destruction by fluid shear stress through a mechano-adaptive RhoA-actomyosin mechanism.
Details
- Title: Subtitle
- Survival of the resilient: Mechano-adaptation of circulating tumor cells to fluid shear stress
- Creators
- Devon L. Moose - University of IowaMichael D. Henry - Roy J. and Lucille A. Carver College of Medicine
- Resource Type
- Journal article
- Publication Details
- Molecular & cellular oncology, Vol.7(4), pp.1766338-1766338
- Publisher
- Taylor & Francis
- DOI
- 10.1080/23723556.2020.1766338
- PMID
- 32944626
- PMCID
- PMC7469561
- ISSN
- 2372-3556
- eISSN
- 2372-3556
- Language
- English
- Date published
- 07/03/2020
- Academic Unit
- Molecular Physiology and Biophysics; Pathology; Radiation Oncology
- Record Identifier
- 9984302998302771
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