Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer

Brian B Hughley; Steven M Sperry; Timothy A Thomsen; Mary E Charlton; Nitin A Pagedar

doi:10.1002/hed.24565

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Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer

Journal article

Peer reviewed

Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer

Brian B Hughley, Steven M Sperry, Timothy A Thomsen, Mary E Charlton and Nitin A Pagedar

Head & neck, Vol.39(2), pp.215-218

02/2017

DOI: 10.1002/hed.24565

PMCID: PMC5844569

PMID: 27507712

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https://www.ncbi.nlm.nih.gov/pmc/articles/5844569View

Open Access

Abstract

This study is an evaluation of survival in patients with upper aerodigestive tract (UADT) cancer who did not receive guideline-directed therapy. The National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) database was examined to identify patients with invasive cancer of the UADT. Patients were classified as "untreated" if they received neither surgery nor radiotherapy. Kaplan-Meier observed survival estimates were computed and stage-specific actuarial estimates of relative survival were computed. Of 3589 untreated patients, 13.7% were black, compared to 9.5% white, and 9.2% all other races (p <.0001). Patients with stage IV disease were more likely to be untreated than those with stage I disease (11.9% vs 3.8%; p <.0001). Median survival was 39 months for treated patients and 4 months for untreated patients. The median survival for untreated patients was 4 months. Stage, race, and primary site were independently associated with untreated status. © 2016 Wiley Periodicals, Inc. Head Neck 39: 215-218, 2017.

Geriatric Assessment

SEER Program

Risk Assessment

United States

Humans

Male

Cause of Death

Watchful Waiting - methods

Neoplasm Invasiveness - pathology

Survival Analysis

Aged, 80 and over

Female

Head and Neck Neoplasms - diagnosis

Aged

Retrospective Studies

Head and Neck Neoplasms - mortality

Neoplasm Staging

Cohort Studies

Details

Title: Subtitle: Survival outcomes in elderly patients with untreated upper aerodigestive tract cancer
Creators: Brian B Hughley - Department of Otolaryngology - Head and Neck Surgery, University of Alabama - Birmingham, Birmingham, Alabama
Steven M Sperry - Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, Iowa
Timothy A Thomsen - Department of Internal Medicine - Palliative Care Program, University of Iowa, Iowa City, Iowa
Mary E Charlton - Department of Epidemiology, University of Iowa, Iowa City, Iowa
Nitin A Pagedar - Department of Otolaryngology - Head and Neck Surgery, University of Iowa, Iowa City, Iowa
Resource Type: Journal article
Publication Details: Head & neck, Vol.39(2), pp.215-218
DOI: 10.1002/hed.24565
PMID: 27507712
PMCID: PMC5844569
NLM abbreviation: Head Neck
ISSN: 1097-0347
eISSN: 1097-0347
Publisher: United States
Grant note: P30 CA086862 / NCI NIH HHS
Language: English
Date published: 02/2017
Academic Unit: Health Management and Policy; Epidemiology; Orthopedics and Rehabilitation; General Internal Medicine; Otolaryngology; Internal Medicine
Record Identifier: 9983996061302771

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