Journal article
Susceptibilities of Oral Bacteria and Yeast to Mammalian Cathelicidins
Antimicrobial agents and chemotherapy, Vol.45(11), pp.3216-3219
Note
11/2001
DOI: 10.1128/AAC.45.11.3216-3219.2001
PMCID: PMC90809
PMID: 11600383
Abstract
The effects of cathelicidins against oral bacteria and clinically important oral yeasts are not known. We tested the susceptibilities of
Actinobacillus actinomycetemcomitans
,
Fusobacterium nucleatum
,
Porphyromonas gingivalis
,
Streptococcus sanguis
,
Candida krusei
,
Candida tropicalis
and
Candida albicans
to the following cathelicidins: FALL39, SMAP29, and CAP18. SMAP29 and CAP18 were antimicrobial, whereas FALL39 did not exhibit antimicrobial activity. Future studies are needed to determine the potential use of these antimicrobial peptides in prevention and treatment of oral infections.
Details
- Title: Subtitle
- Susceptibilities of Oral Bacteria and Yeast to Mammalian Cathelicidins
- Creators
- Janet M Guthmiller - Departments of PeriodonticsKaaren G Vargas - Departments of PeriodonticsRupasree Srikantha - Departments of PeriodonticsLori L Schomberg - Departments of PeriodonticsPaula L Weistroffer - Departments of PeriodonticsPaul B McCray - Departments of PeriodonticsBrian F Tack - Departments of Periodontics
- Resource Type
- Journal article
- Publication Details
- Antimicrobial agents and chemotherapy, Vol.45(11), pp.3216-3219
- Series
- Note
- DOI
- 10.1128/AAC.45.11.3216-3219.2001
- PMID
- 11600383
- PMCID
- PMC90809
- NLM abbreviation
- Antimicrob Agents Chemother
- ISSN
- 0066-4804
- eISSN
- 1098-6596
- Publisher
- American Society for Microbiology
- Language
- English
- Date published
- 11/2001
- Academic Unit
- Microbiology and Immunology; Pulmonary Medicine; Stead Family Department of Pediatrics; Periodontics; Internal Medicine
- Record Identifier
- 9984093211102771
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