Journal article
Susceptibility of coagulase-negative staphylococcal nosocomial bloodstream isolates to the chlorhexidine/silver sulfadiazine-impregnated central venous catheter
American Journal of Infection Control, Vol.32(8), pp.486-488
2004
DOI: 10.1016/j.ajic.2004.06.002
PMID: 15573055
Abstract
Nosocomial bloodstream infections (BSIs) are important causes of morbidity and mortality, and coagulase-negative staphylococci (CNS) are the most common pathogens. Second generation, central venous catheters impregnated with chlorhexidine and silver sulfadiazine were recently introduced for the prevention of catheter-related infections and appear to be effective in reducing the incidence of both colonization and catheter related BSI. 1 However, the potential for emergence to biocides has been a concern. A recent study evaluating the in vitro susceptibility of epidemiologically important pathogens found a statistically significant inverse correlation between intensity of chlorhexidine use and the overall susceptibility of all organisms tested to this agent. 2 Because of an increase in the incidence of CNS BSIs in our 12-bed medical intensive care unit (MICU) from 6.6/1000 catheter days in 2000 to 12.7/1000 catheter days in 2003, we evaluated changes in the epidemiology and susceptibility of CNS following the
Details
- Title: Subtitle
- Susceptibility of coagulase-negative staphylococcal nosocomial bloodstream isolates to the chlorhexidine/silver sulfadiazine-impregnated central venous catheter
- Creators
- Adriana E RosatoSandra M TallentMichael B EdmondGonzalo M.L Bearman
- Resource Type
- Journal article
- Publication Details
- American Journal of Infection Control, Vol.32(8), pp.486-488
- DOI
- 10.1016/j.ajic.2004.06.002
- PMID
- 15573055
- NLM abbreviation
- Am J Infect Control
- ISSN
- 0196-6553
- eISSN
- 1527-3296
- Language
- English
- Date published
- 2004
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9983905532802771
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