Journal article
Sustained Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Associated Hospitalizations Among Adults - United States, March-July 2021
MMWR. Morbidity and mortality weekly report, Vol.70(34), pp.1156-1162
08/27/2021
DOI: 10.15585/MMWR.MM7034E2
PMCID: PMC8389395
PMID: 34437524
Abstract
What is already known about this topic?
COVID-19 mRNA vaccines provide strong protection against severe COVID-19; however, the duration of protection is uncertain.
What is added by this report?
Among 1,129 patients who received 2 doses of a mRNA vaccine, no decline in vaccine effectiveness against COVID-19 hospitalization was observed over 24 weeks. Vaccine effectiveness was 86% 2-12 weeks after vaccination and 84% at 13-24 weeks. Vaccine effectiveness was sustained among groups at risk for severe COVID-19.
What are the implications for public health practice?
mRNA vaccine effectiveness against COVID-19-associated hospitalizations was sustained over 24 weeks; ongoing monitoring is needed as new SARS- CoV-2 variants emerge. To reduce hospitalization, all eligible persons should be offered COVID-19 vaccination.
Details
- Title: Subtitle
- Sustained Effectiveness of Pfizer-BioNTech and Moderna Vaccines Against COVID-19 Associated Hospitalizations Among Adults - United States, March-July 2021
- Creators
- Mark W. Tenforde - Centers for Disease Control and PreventionWesley H. Self - Vanderbilt UniversityEric A. Naioti - Centers for Disease Control and PreventionAdit A. Ginde - University of Colorado DenverDavid J. Douin - University of Colorado DenverSamantha M. Olson - Centers for Disease Control and PreventionH. Keipp Talbot - Vanderbilt UniversityJonathan D. Casey - Vanderbilt UniversityNicholas M. Mohr - University of IowaAnne Zepeski - University of IowaManjusha Gaglani - Texas A&M UniversityTresa McNeal - Baylor Medical Center at GarlandShekhar Ghamande - Baylor Medical Center at GarlandNathan I. Shapiro - Harvard UniversityKevin W. Gibbs - Wake Forest UniversityD. Clark Files - Wake Forest UniversityDavid N. Hager - Johns Hopkins UniversityArber Shehu - Johns Hopkins UniversityMatthew E. Prekker - Hennepin County Medical CenterHeidi L. Erickson - Hennepin County Medical CenterMichelle N. Gong - Yeshiva UniversityAmira Mohamed - Yeshiva UniversityDaniel J. Henning - University of WashingtonJay S. Steingrub - Tufts UniversityIthan D. Peltan - University of UtahSamuel M. Brown - University of UtahEmily T. Martin - University of MichiganArnold S. Monto - University of MichiganAkram Khan - Oregon Health & Science UniversityCatherine L. Hough - Oregon Health & Science UniversityLaurence W. Busse - Emory UniversityCaitlin C. ten Lohuis - Emory UniversityAbhijit Duggal - Cleveland ClinicJennifer G. Wilson - Stanford UniversityAlexandra June Gordon - Stanford UniversityNida Qadir - University of California, Los AngelesSteven Y. Chang - University of California, Los AngelesChristopher Mallow - University of MiamiCarolina Rivas - University of MiamiHilary M. Babcock - Washington University in St. LouisJennie H. Kwon - Washington University in St. LouisMatthew C. Exline - The Ohio State UniversityNatasha Halasa - Vanderbilt UniversityJames D. Chappell - Vanderbilt UniversityAdam S. Lauring - University of MichiganCarlos G. Grijalva - Vanderbilt UniversityTodd W. Rice - Vanderbilt UniversityIan D. Jones - Vanderbilt UniversityWilliam B. Stubblefield - Vanderbilt UniversityAdrienne Baughman - Vanderbilt UniversityKelsey N. Womack - Vanderbilt UniversityChristopher J. Lindsell - Vanderbilt UniversityKimberly W. Hart - Vanderbilt UniversityYuwei Zhu - Vanderbilt UniversityMeagan Stephenson - Centers for Disease Control and PreventionStephanie J. Schrag - Centers for Disease Control and PreventionMiwako Kobayashi - Centers for Disease Control and PreventionJennifer R. Verani - Centers for Disease Control and PreventionManish M. Patel - Centers for Disease Control and PreventionIVY Network Investigators
- Resource Type
- Journal article
- Publication Details
- MMWR. Morbidity and mortality weekly report, Vol.70(34), pp.1156-1162
- DOI
- 10.15585/MMWR.MM7034E2
- PMID
- 34437524
- PMCID
- PMC8389395
- NLM abbreviation
- MMWR Morb Mortal Wkly Rep
- ISSN
- 0149-2195
- eISSN
- 1545-861X
- Publisher
- Centers Disease Control & Prevention
- Number of pages
- 7
- Language
- English
- Date published
- 08/27/2021
- Academic Unit
- Epidemiology; Emergency Medicine; Anesthesia; Injury Prevention Research Center
- Record Identifier
- 9984296133902771
Metrics
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