Journal article
Sustained blood pressure control following discontinuation of a pharmacist intervention
The journal of clinical hypertension (Greenwich, Conn.), Vol.13(6), pp.431-437
06/2011
DOI: 10.1111/j.1751-7176.2011.00435.x
PMCID: PMC4126237
PMID: 21649843
Abstract
Team-based care can improve hypertension control. The purpose of the present study was to evaluate blood pressure (BP) control 18 months following the discontinuation of a physician-pharmacist collaborative intervention. This was a retrospective analysis of patients who had previously participated in a prospective, cluster randomized, controlled clinical trial. Six community-based family medicine offices were randomized to control or intervention groups. Research nurses measured BPs using an automated device during the prospective trial. The research nurses then abstracted data from medical records, including BPs, medications, changes in therapy, and laboratory values for 18 months following the discontinuation of the 6-month prospective trial. The study included 228 patients in the control (n = 146) or intervention (n = 82) groups. The control group contained more patients with diabetes or chronic kidney disease (P < .013), were older (P = .047), and had more coexisting conditions (P < .001) than the intervention group. Systolic BP 9 months following discontinuation of the physician-pharmacist intervention was 137.2 ± 18.2 mm Hg and 129.8 ± 13.3 mm Hg in the control and intervention groups, respectively (P = .0015). BP control was maintained in 61 (41.8%) control patients and 55 (67.1%) intervention patients (P = .0003). At 18 months post-intervention, systolic BP was 138.1 ± 20.4 mm Hg and 130.0 ± 16.0 mm Hg in the control and intervention groups, respectively (P = .023). BP control was maintained in 53 (36.3%) control patients and 55 (67.1%) intervention patients at 18 months post-intervention (P < .0001). A sensitivity analysis was conducted to address the uneven distribution of patients with diabetes or chronic kidney disease, and the differences between groups were still significant. BP control rates remained significantly higher following a physician-pharmacist intervention compared with usual care for 18 months after discontinuation of the intervention. This model has the potential value as a useful long-term strategy to benefit patients with hypertension.
Details
- Title: Subtitle
- Sustained blood pressure control following discontinuation of a pharmacist intervention
- Creators
- Danielle M Wentzlaff - Department of Pharmacy Practice and Science, College of Pharmacy, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, IA, USABarry L CarterGail ArderyCarrie L FranciscusWilliam R DoucetteElizabeth A ChrischillesKurt A RosenkransLucinda M Buys
- Resource Type
- Journal article
- Publication Details
- The journal of clinical hypertension (Greenwich, Conn.), Vol.13(6), pp.431-437
- DOI
- 10.1111/j.1751-7176.2011.00435.x
- PMID
- 21649843
- PMCID
- PMC4126237
- NLM abbreviation
- J Clin Hypertens (Greenwich)
- ISSN
- 1751-7176
- eISSN
- 1751-7176
- Publisher
- United States
- Grant note
- R01 HL069801 / NHLBI NIH HHS R01 HL070740 / NHLBI NIH HHS U18 HS016094 / AHRQ HHS 5U18HS016094 / AHRQ HHS R01 HL69801 / NHLBI NIH HHS
- Language
- English
- Date published
- 06/2011
- Academic Unit
- Pharmacy; Epidemiology; Family and Community Medicine; Pharmacy Practice and Science
- Record Identifier
- 9983996094702771
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