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Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) study
Journal article   Open access   Peer reviewed

Sustained effect of intensive treatment of type 1 diabetes mellitus on development and progression of diabetic nephropathy: The Epidemiology of Diabetes Interventions and Complications (EDIC) study

Michael W Steffes, Blanche M Chavers, Mark E Molitch, Patricia A Cleary and Writing Team for the Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Research Group
JAMA : the journal of the American Medical Association, Vol.290(16), pp.2159-2167
10/22/2003
DOI: 10.1001/jama.290.16.2159
PMCID: PMC2622725
PMID: 14570951
url
https://doi.org/10.1001/jama.290.16.2159View
Published (Version of record) Open Access

Abstract

Steffes et al determine the long-term effects of intensive vs. conventional treatment during the Diabetes Control and Complications Trial on kidney function during the Epidemiology of Diabetes Interventions and Complications study. The persistent beneficial effects on albumin excretion and the reduced incidence of hypertension suggest that previous intensive treatment of diabetes with near-normal glycemia delay the progression of diabetes nephropathy.
Clinical Trials Diabetes Epidemiology Medical Treatment Side effects

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