Swine Workers and Swine Influenza Virus Infections

Gregory C Gray; Troy McCarthy; Ana W Capuano; Sharon F Setterquist; Christopher W Olsen; Michael C Alavanja; Charles F Lynch

doi:10.3201/eid1312.061323

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Swine Workers and Swine Influenza Virus Infections

Journal article

Open access

Peer reviewed

Swine Workers and Swine Influenza Virus Infections

Gregory C Gray, Troy McCarthy, Ana W Capuano, Sharon F Setterquist, Christopher W Olsen, Michael C Alavanja and Charles F Lynch

Emerging infectious diseases, Vol.13(12), pp.1871-1878

12/2007

DOI: 10.3201/eid1312.061323

PMCID: PMC2876739

PMID: 18258038

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Abstract

Swine workers and their spouses are at markedly increased risk of acquiring swine influenza virus infections. In 2004, 803 rural Iowans from the Agricultural Health Study were enrolled in a 2-year prospective study of zoonotic influenza transmission. Demographic and occupational exposure data from enrollment, 12-month, and 24-month follow-up encounters were examined for association with evidence of previous and incident influenza virus infections. When proportional odds modeling with multivariable adjustment was used, upon enrollment, swine-exposed participants (odds ratio [OR] 54.9, 95% confidence interval [CI] 13.0–232.6) and their nonswine-exposed spouses (OR 28.2, 95% CI 6.1–130.1) were found to have an increased odds of elevated antibody level to swine influenza (H1N1) virus compared with 79 nonexposed University of Iowa personnel. Further evidence of occupational swine influenza virus infections was observed through self-reported influenza-like illness data, comparisons of enrollment and follow-up serum samples, and the isolation of a reassortant swine influenza (H1N1) virus from an ill swine farmer. Study data suggest that swine workers and their nonswine-exposed spouses are at increased risk of zoonotic influenza virus infections.

agriculture

communicable diseases

disease outbreaks

emerging

epidemiology

Influenza

influenza A virus

occupational exposure

porcine

Research

seroepidemiologic studies

zoonoses

Details

Title: Subtitle: Swine Workers and Swine Influenza Virus Infections
Creators: Gregory C Gray - University of Iowa College of Public Health, Iowa City, Iowa, USA
Troy McCarthy - University of Iowa College of Public Health, Iowa City, Iowa, USA
Ana W Capuano - University of Iowa College of Public Health, Iowa City, Iowa, USA
Sharon F Setterquist - University of Iowa College of Public Health, Iowa City, Iowa, USA
Christopher W Olsen - University of Wisconsin-Madison School of Veterinary Medicine, Madison, Wisconsin, USA
Michael C Alavanja - National Cancer Institute, Bethesda, Maryland, USA
Charles F Lynch - University of Iowa College of Public Health, Iowa City, Iowa, USA
Resource Type: Journal article
Publication Details: Emerging infectious diseases, Vol.13(12), pp.1871-1878
DOI: 10.3201/eid1312.061323
PMID: 18258038
PMCID: PMC2876739
NLM abbreviation: Emerg Infect Dis
ISSN: 1080-6040
eISSN: 1080-6059
Publisher: Centers for Disease Control and Prevention
Language: English
Date published: 12/2007
Academic Unit: Epidemiology
Record Identifier: 9984214848202771

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