Journal article
Symptoms as predictors of response to amitriptyline and nortriptyline: The plasma level variable
Journal of affective disorders, Vol.2(1), pp.27-35
1980
DOI: 10.1016/0165-0327(80)90019-1
PMID: 6448878
Abstract
Data collected to define therapeutic plasma levels for amitriptyline and nortriptyline were re-analyzed to test endogenous and non-endogenous symptoms as response predictors while controlling for plasma level variable. The selection criteria limited the range of historical predictors. Initial symptom quality was not predictive of outcome for the entire group of 44 patients or for the 27 with therapeutic plasma levels. Delusions were not associated with poor outcome. The authors conclude that historical components of the endogenous—non-endogenous distinction (e.g., premorbid personality, stability of symptoms over time, quality of remissions) may be more important as response predictors.
Details
- Title: Subtitle
- Symptoms as predictors of response to amitriptyline and nortriptyline: The plasma level variable
- Creators
- William Coryell - Department of Psychiatry, University of Iowa College of Medicine, Iowa City, IA, USAVincent E Ziegler - Private practice, Crestview Hills, KY, USAJohn T Biggs - Department of Psychiatry, Washington University, St. Louis, MO, U.S.A
- Resource Type
- Journal article
- Publication Details
- Journal of affective disorders, Vol.2(1), pp.27-35
- DOI
- 10.1016/0165-0327(80)90019-1
- PMID
- 6448878
- NLM abbreviation
- J Affect Disord
- ISSN
- 0165-0327
- eISSN
- 1573-2517
- Publisher
- Elsevier B.V
- Language
- English
- Date published
- 1980
- Academic Unit
- Psychiatry
- Record Identifier
- 9984003430802771
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