Journal article
Synchronous tumors of the pancreas and the gallbladder: a case report with targeted NGS evaluation
Annals of translational medicine, Vol.7(22), pp.696-696
11/01/2019
DOI: 10.21037/atm.2019.10.107
PMCID: PMC6944562
PMID: 31930097
Abstract
Synchronous tumors of the pancreas and gallbladder are rare and often attributed to an abnormal pancreato-biliary junction, which results in a persistent reflux of pancreatic secretions leading to chronic biliary inflammation. We present the case of a 73-year-old woman with synchronous lesions of the pancreas and gallbladder initially considered as two primary localized cancers and treated with curative intent. At relapse, targeted next generation sequencing (NGS), performed in search of potential therapeutic targets, uncovered the fact that the two lesions appeared to be clonally related. This case illustrates the problem of synchronous lesions of the pancreas and gallbladder. New pathologic assessments with comparative molecular analysis of mutational profiles may be helpful in this context.
Details
- Title: Subtitle
- Synchronous tumors of the pancreas and the gallbladder: a case report with targeted NGS evaluation
- Creators
- Aurelie Sivade - University of LausanneChristine Sempoux - University of LausanneIoannis Voutsadakis - NOSM UniversityChristophe Brunel - University of LausanneNermin Halkic - University of LausanneSebastian Godat - University of LausanneRafael Duran - University of LausanneAntonia Digklia - University of Lausanne
- Resource Type
- Journal article
- Publication Details
- Annals of translational medicine, Vol.7(22), pp.696-696
- DOI
- 10.21037/atm.2019.10.107
- PMID
- 31930097
- PMCID
- PMC6944562
- NLM abbreviation
- Ann Transl Med
- ISSN
- 2305-5839
- eISSN
- 2305-5839
- Publisher
- AME Publishing Company
- Language
- English
- Date published
- 11/01/2019
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984808212002771
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