Journal article
Synthesis and Biological Evaluation of a Phosphonate Phosphoantigen Prodrug
Phosphorus, Sulfur, and Silicon and the Related Elements: 20th International Conference on Phosphorus Chemistry (ICPC-2014), Vol.190(5-6), pp.751-753
06/03/2015
DOI: 10.1080/10426507.2014.974099
Abstract
We have recently reported the synthesis of the first known phosphoantigen prodrug, and have demonstrated excellent gains in potency through delivery of the phosphoantigen to the intracellular domain of BTN3A1.
Details
- Title: Subtitle
- Synthesis and Biological Evaluation of a Phosphonate Phosphoantigen Prodrug
- Creators
- Chia-Hung Christine Hsiao - Department of Pharmaceutical Sciences, University of ConnecticutXiaochen Lin - Department of Pharmaceutical Sciences, University of ConnecticutRocky J Barney - Department of Chemistry, Western Wyoming Community CollegeRebekah R Shippy - Department of Chemistry, University of IowaJin Li - Department of Pharmaceutical Sciences, University of ConnecticutOlga Vinogradova - Department of Pharmaceutical Sciences, University of ConnecticutDavid F Wiemer - Department of Pharmacology, University of IowaAndrew J Wiemer - Department of Pharmaceutical Sciences, University of Connecticut
- Resource Type
- Journal article
- Publication Details
- Phosphorus, Sulfur, and Silicon and the Related Elements: 20th International Conference on Phosphorus Chemistry (ICPC-2014), Vol.190(5-6), pp.751-753
- Publisher
- Taylor & Francis
- DOI
- 10.1080/10426507.2014.974099
- ISSN
- 1042-6507
- eISSN
- 1563-5325
- Language
- English
- Date published
- 06/03/2015
- Academic Unit
- Chemistry; Neuroscience and Pharmacology
- Record Identifier
- 9983985933902771
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