Journal article
Synthesis and identification of highly toxic polybrominated biphenyls in the fire retardant Firemaster BP-6
Journal of agricultural and food chemistry, Vol.32(5), pp.1107-1111
09/01/1984
DOI: 10.1021/jf00125a045
Abstract
The identity of over 91% of the polybrominated biphenyl (PBB) components present in fire Master BP-6 was determined by capillary gas chromatography (GC) and GC-mass spectrometry (MS) with 22 individual PBB congeners as reference standards. There was an excellent correlation between the observed retention times of the individual PBBs (and of the corresponding GC peaks in fire Master) and the expected retention times calculated from the degree of bromination and substituent orientation for the PBB standards. Previous studies indicate that the more toxic PBBs are also inducers of rat hepatic microsomal aryl hydrocarbon hydroxylase (AHH). This paper reports the GC and GC-MS identification of seven additional PBBs in fire Master that also induce aryl hydrocarbon hydroxylase. Included in this group of seven potentially toxic PBBs are the coplanar 3, 3', 4', 4'-tetra-, 3, 3-, 4, 4-, 5-penta-, and 3, 3-, 4, 4-, 5, 5'-hexabromobiphenyls, which represent the most toxic group of PBB congeners identified in fire Master. © 1984, American Chemical Society. All rights reserved.
Details
- Title: Subtitle
- Synthesis and identification of highly toxic polybrominated biphenyls in the fire retardant Firemaster BP-6
- Creators
- Larry W Robertson - Texas A&M UniversityStephen H Safe - Houston MethodistAndrew Parkinson - RocheEdo Pellizzari - RTI InternationalCarol PochiniMichael D Mullin
- Resource Type
- Journal article
- Publication Details
- Journal of agricultural and food chemistry, Vol.32(5), pp.1107-1111
- Publisher
- American Chemical Society
- DOI
- 10.1021/jf00125a045
- ISSN
- 0021-8561
- eISSN
- 1520-5118
- Language
- English
- Date published
- 09/01/1984
- Academic Unit
- Occupational and Environmental Health
- Record Identifier
- 9984364434002771
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