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Synthesis of (23R)- and (23S)-methylcholesterol
Journal article   Peer reviewed

Synthesis of (23R)- and (23S)-methylcholesterol

Huiting Li, Ian J Massey, Dale C Swenson, William L Duax and Carl Djerassi
Journal of organic chemistry, Vol.48(1), pp.48-54
01/01/1983
DOI: 10.1021/jo00149a010

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Abstract

23-Methylcholesterol is likely to exist in nature. In order to facilitate its recognition, (231?)- and (23S)-methylcholesterol have been synthesized, and the absolute configuration has been established by X-ray analysis. Substantial differences were encountered in comparing the course of catalytic hydrogenation and of double-bond isomerization of 22- and 23-methylenecholesterol.

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