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Synthesis of biotinylated OSW-1
Journal article   Peer reviewed

Synthesis of biotinylated OSW-1

Ying Kang, Changgang Lou, Kausar Begam Riaz Ahmed, Peng Huang and Zhendong Jin
Bioorganic & medicinal chemistry letters, Vol.19(17), pp.5166-5168
2009
DOI: 10.1016/j.bmcl.2009.07.062
PMCID: PMC2762400
PMID: 19640708

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Abstract

OSW-1 is a highly potent anticancer natural saponin with unknown mode of action. To determine its cellular target(s) biotinylated OSW-1 was successfully synthesized in nine steps. OSW-1 is a highly potent anticancer natural saponin with an unknown mode of action. To determine its cellular target(s) biotinylated OSW-1 was successfully synthesized in nine steps.
Biotinylated Natural product OSW-1 Saponin Synthesis

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