Synthesis of chroman aldehydes that inhibit HIV

Journal article

Open access

Peer reviewed

George A Kraus, John Mengwasser, Wendy Maury and ChoonSeok Oh

Bioorganic & medicinal chemistry letters, Vol.21(5), pp.1399-1401

03/01/2011

DOI: 10.1016/j.bmcl.2011.01.031

PMCID: PMC3725577

PMID: 21306897

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https://doi.org/10.1016/j.bmcl.2011.01.031View

Published (Version of record) Open Access

Chroman aldehydes bearing an acetyl group plus alkoxyl or hydroxyl groups inhibit HIV infectivity in HeLa37 cells.

Cell Line

Antiviral Agents - pharmacology

Aldehydes - chemical synthesis

Humans

HIV - drug effects

Chromans - pharmacology

Antiviral Agents - chemistry

Aldehydes - pharmacology

Antiviral Agents - chemical synthesis

Inhibitory Concentration 50

Chromans - chemical synthesis

HIV Infections - drug therapy

Molecular Structure

Chromans - chemistry

Aldehydes - chemistry

Title: Subtitle: Synthesis of chroman aldehydes that inhibit HIV
Creators: George A Kraus - Department of Chemistry, Iowa State University, Ames, IA 50011, USA. gakraus@iastate.edu
John Mengwasser
Wendy Maury
ChoonSeok Oh
Resource Type: Journal article
Publication Details: Bioorganic & medicinal chemistry letters, Vol.21(5), pp.1399-1401
DOI: 10.1016/j.bmcl.2011.01.031
PMID: 21306897
PMCID: PMC3725577
NLM abbreviation: Bioorg Med Chem Lett
ISSN: 0960-894X
eISSN: 1464-3405
Grant note: P50 AT004155 / NCCIH NIH HHS
Language: English
Date published: 03/01/2011
Academic Unit: Microbiology and Immunology
Record Identifier: 9984083285502771

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