Journal article
Synthesis of phosphonates from .alpha.-hydroxy carbonyl compounds and dialkyl phosphorochloridites
Journal of organic chemistry, Vol.54(3), pp.627-631
02/01/1989
DOI: 10.1021/jo00264a023
Abstract
In the presence of a Lewis acid, dialkyl phosphorochloridites react with a-hydroxy ketones to afford 0-keto phosphonates and with a-hydroxy esters to afford phosphonic acid diesters. These reactions provide convenient access to a variety of structures, including β-keto phosphonates that are fully substituted at the a-carbon. © 1989, American Chemical Society. All rights reserved.
Details
- Title: Subtitle
- Synthesis of phosphonates from .alpha.-hydroxy carbonyl compounds and dialkyl phosphorochloridites
- Creators
- Vassilios RoussisDavid F Wiemer
- Resource Type
- Journal article
- Publication Details
- Journal of organic chemistry, Vol.54(3), pp.627-631
- Publisher
- American Chemical Society
- DOI
- 10.1021/jo00264a023
- ISSN
- 0022-3263
- eISSN
- 1520-6904
- Language
- English
- Date published
- 02/01/1989
- Academic Unit
- Neuroscience and Pharmacology; Chemistry
- Record Identifier
- 9984216718802771
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