Journal article
Synthesis of the schweinfurthin hexahydroxanthene core through Shi epoxidation
Tetrahedron letters, Vol.49(3), pp.516-519
2008
DOI: 10.1016/j.tetlet.2007.11.086
Abstract
Use of a Shi epoxidation for introduction of chirality in a key epoxide intermediate, together with revised protecting group tactics, has allowed an efficient synthesis of the hexahydroxanthene subunit common to the natural schweinfurthin F and the synthetic analogue 3-deoxyschweinfurthin B. Use of a Shi epoxidation for introduction of chirality in a key epoxide intermediate, together with revised protecting group tactics, has allowed an efficient synthesis of the hexahydroxanthene subunit common to the natural schweinfurthin F and the synthetic analogue 3-deoxyschweinfurthin B.
Details
- Title: Subtitle
- Synthesis of the schweinfurthin hexahydroxanthene core through Shi epoxidation
- Creators
- Jeffrey D NeighborsNolan R MenteKelly D BossDonald W ZehnderDavid F Wiemer
- Resource Type
- Journal article
- Publication Details
- Tetrahedron letters, Vol.49(3), pp.516-519
- Publisher
- Elsevier Ltd
- DOI
- 10.1016/j.tetlet.2007.11.086
- ISSN
- 0040-4039
- eISSN
- 1873-3581
- Language
- English
- Date published
- 2008
- Academic Unit
- Neuroscience and Pharmacology; Chemistry
- Record Identifier
- 9983985971502771
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