Synthetic Biology Open Language (SBOL) Version 2.1.0

Jacob Beal; Robert Sidney Cox; Raik Grunberg; James McLaughlin; Tramy Nguyen; Bryan Bartley; Michael Bissell; Kiri Choi; Kevin Clancy; Chris Macklin; Curtis Madsen; Goksel Misirli; Ernst Oberortner; Matthew Pocock; Nicholas Roehner; Meher Samineni; Michael Zhang; Zhen Zhang; Zach Zundel; John H. Gennari; Chris Myers; Herbert Sauro; Anil Wipat

doi:10.2390/biecoll-jib-2016-291

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Synthetic Biology Open Language (SBOL) Version 2.1.0

Journal article

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Synthetic Biology Open Language (SBOL) Version 2.1.0

Jacob Beal, Robert Sidney Cox, Raik Grunberg, James McLaughlin, Tramy Nguyen, Bryan Bartley, Michael Bissell, Kiri Choi, Kevin Clancy, Chris Macklin, …

Journal of integrative bioinformatics, Vol.13(3), pp.30-132

12/18/2016

DOI: 10.2390/biecoll-jib-2016-291

PMID: 28187407

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Abstract

Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.1 of SBOL that builds upon version 2.0 published in last year's JIB special issue. In particular, SBOL 2.1 includes improved rules for what constitutes a valid SBOL document, new role fields to simplify the expression of sequence features and how components are used in context, and new best practices descriptions to improve the exchange of basic sequence topology information and the description of genetic design provenance, as well as miscellaneous other minor improvements.

Life Sciences & Biomedicine

Mathematical & Computational Biology

Science & Technology

Details

Title: Subtitle: Synthetic Biology Open Language (SBOL) Version 2.1.0
Creators: Jacob Beal - Raytheon
Robert Sidney Cox - Kobe University
Raik Grunberg - King Abdullah Univ Sci & Technol, Thuwal, Saudi Arabia
James McLaughlin - Newcastle University
Tramy Nguyen - University of Utah
Bryan Bartley - University of Washington
Michael Bissell - Amyris
Kiri Choi - University of Washington
Kevin Clancy - ThermoFisher Sci, Waltham, MA USA
Chris Macklin - Amyris
Curtis Madsen - Boston University
Goksel Misirli - Newcastle University
Ernst Oberortner - Joint Genome Institute
Matthew Pocock - ATE
Nicholas Roehner - Boston University
Meher Samineni - University of Utah
Michael Zhang - University of Utah
Zhen Zhang - Univ S Florida, Tampa, FL USA
Zach Zundel - University of Utah
John H. Gennari - University of Washington
Chris Myers - University of Utah
Herbert Sauro - University of Washington
Anil Wipat - Newcastle University
Resource Type: Journal article
Publication Details: Journal of integrative bioinformatics, Vol.13(3), pp.30-132
Publisher: IMBIO E V
DOI: 10.2390/biecoll-jib-2016-291
PMID: 28187407
ISSN: 1613-4516
eISSN: 1613-4516
Number of pages: 103
Language: English
Date published: 12/18/2016
Academic Unit: Electrical and Computer Engineering
Record Identifier: 9984627192702771

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