Synthetic Biology Open Language (SBOL) Version 2.0.0

Bryan Bartley; Jacob Beal; Kevin Clancy; Goksel Misirli; Nicholas Roehner; Ernst Oberortner; Matthew Pocock; Michael Bissell; Curtis Madsen; Tramy Nguyen; Zhen Zhang; John H. Gennari; Chris Myers; Anil Wipat; Herbert Sauro

doi:10.2390/biecoll-jib-2015-272

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Synthetic Biology Open Language (SBOL) Version 2.0.0

Journal article

Peer reviewed

Synthetic Biology Open Language (SBOL) Version 2.0.0

Bryan Bartley, Jacob Beal, Kevin Clancy, Goksel Misirli, Nicholas Roehner, Ernst Oberortner, Matthew Pocock, Michael Bissell, Curtis Madsen, Tramy Nguyen, …

Journal of integrative bioinformatics, Vol.12(2), pp.902-991

09/04/2015

DOI: 10.2390/biecoll-jib-2015-272

PMID: 26528570

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Abstract

Synthetic biology builds upon the techniques and successes of genetics, molecular biology, and metabolic engineering by applying engineering principles to the design of biological systems. The field still faces substantial challenges, including long development times, high rates of failure, and poor reproducibility. One method to ameliorate these problems would be to improve the exchange of information about designed systems between laboratories. The Synthetic Biology Open Language (SBOL) has been developed as a standard to support the specification and exchange of biological design information in synthetic biology, filling a need not satisfied by other pre-existing standards. This document details version 2.0 of SBOL, introducing a standardized format for the electronic exchange of information on the structural and functional aspects of biological designs. The standard has been designed to support the explicit and unambiguous description of biological designs by means of a well defined data model. The standard also includes rules and best practices on how to use this data model and populate it with relevant design details. The publication of this specification is intended to make these capabilities more widely accessible to potential developers and users in the synthetic biology community and beyond.

Life Sciences & Biomedicine

Mathematical & Computational Biology

Science & Technology

Details

Title: Subtitle: Synthetic Biology Open Language (SBOL) Version 2.0.0
Creators: Bryan Bartley - University of Washington
Jacob Beal - Raytheon BBN Technol, Cambridge, MA USA
Kevin Clancy - ThermoFisher Sci, Waltham, MA USA
Goksel Misirli - Newcastle University
Nicholas Roehner - Boston University
Ernst Oberortner - Joint Genome Institute
Matthew Pocock - Newcastle University
Michael Bissell - Amyris (United States)
Curtis Madsen - Newcastle University
Tramy Nguyen - University of Utah
Zhen Zhang - University of Utah
John H. Gennari - University of Washington
Chris Myers - University of Utah
Anil Wipat - Newcastle University
Herbert Sauro - University of Washington
Resource Type: Journal article
Publication Details: Journal of integrative bioinformatics, Vol.12(2), pp.902-991
DOI: 10.2390/biecoll-jib-2015-272
PMID: 26528570
NLM abbreviation: J Integr Bioinform
ISSN: 1613-4516
eISSN: 1613-4516
Publisher: Walter De Gruyter
Number of pages: 90
Grant note: 1356041 / Div Of Biological Infrastructure; National Science Foundation (NSF); NSF - Directorate for Biological Sciences (BIO) 1447689 / Direct For Computer & Info Scie & Enginr; National Science Foundation (NSF); NSF - Directorate for Computer & Information Science & Engineering (CISE)
Language: English
Date published: 09/04/2015
Academic Unit: Electrical and Computer Engineering
Record Identifier: 9984627233802771

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