Syphilitic neuroretinitis

J C Folk; T A Weingeist; J J Corbett; L A Lobes; R C Watzke

doi:10.1016/0002-9394(83)90268-4

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Journal article

Peer reviewed

Syphilitic neuroretinitis

J C Folk, T A Weingeist, J J Corbett, L A Lobes and R C Watzke

American journal of ophthalmology, Vol.95(4), pp.480-486

04/1983

DOI: 10.1016/0002-9394(83)90268-4

PMID: 6837690

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Abstract

Four patients (three men, 32, 43, and 53 years old, and one 37-year-old woman) with syphilitic neuroretinitis had cerebrospinal fluid evidence of neurosyphilis. Therapy failed in one patient given penicillin G benzathine intramuscularly and it may have failed in a second patient. Another treatment failure occurred in a patient given tetracycline orally. Intramuscular penicillin G benzathine or intramuscular penicillin G procaine in doses of less than 2.4 million units/day does not produce spirocheticidal drug levels in the cerebrospinal fluid. All four patients improved after high-dose treatment with aqueous penicillin G.

Penicillin G Benzathine - administration & dosage

Administration, Oral

Humans

Middle Aged

Male

Injections, Intramuscular

Visual Acuity

Syphilis, Latent - complications

Neurosyphilis - complications

Retinitis - drug therapy

Adult

Female

Retinitis - diagnosis

Neurosyphilis - drug therapy

Retinitis - etiology

Tetracycline - administration & dosage

Fluorescein Angiography

Details

Title: Subtitle: Syphilitic neuroretinitis
Creators: J C Folk
T A Weingeist
J J Corbett
L A Lobes
R C Watzke
Resource Type: Journal article
Publication Details: American journal of ophthalmology, Vol.95(4), pp.480-486
Publisher: United States
DOI: 10.1016/0002-9394(83)90268-4
PMID: 6837690
ISSN: 0002-9394
eISSN: 1879-1891
Language: English
Date published: 04/1983
Academic Unit: Ophthalmology and Visual Sciences
Record Identifier: 9983980008102771

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