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Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes
Journal article   Open access

Systematic Complex Haploinsufficiency-Based Genetic Analysis of Candida albicans Transcription Factors: Tools and Applications to Virulence-Associated Phenotypes

Virginia E Glazier, Thomas Murante, Kristy Koselny, Daniel Murante, Marisol Esqueda, Gina A Wall, Melanie Wellington, Chiung-Yu Hung, Anuj Kumar and Damian J. Krysan
G3 : genes - genomes - genetics, Vol.8(4), pp.1299-1314
03/28/2018
DOI: 10.1534/g3.117.300515
PMCID: PMC5873919
PMID: 29472308
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Systematic Complex Haploinsufficiency-Based Genetic Analysis of C2.02 MBDownloadView
Published (Version of record)CC BY V4.0 Open Access
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https://doi.org/10.1534/g3.117.300515View
Published (Version of record)G3 (Bethesda). 2018 Mar 28;8(4):1299-1314.

Abstract

Genetic interaction analysis is a powerful approach to the study of complex biological processes that are dependent on multiple genes. Because of the largely diploid nature of the human fungal pathogen

Biofilms Medical Genetics Pediatrics Phenotype Plasmids Cell and Developmental Biology Genetic Processes Infectious Disease Animals Candida albicans Candidiasis Disease Models Animal Fungal Proteins Gene Deletion Gene Library Gene Regulatory Networks Haploinsufficiency Heterozygote Plankton Transcription Factors Virulence

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