Journal article
Systematic literature review of evidence in amyloid light-chain amyloidosis
Journal of comparative effectiveness research, Vol.11(6), pp.451-472
04/2022
DOI: 10.2217/cer-2021-0261
PMID: 35188424
Abstract
Treatment of amyloid light-chain (AL) amyloidosis, a rare disease with a <5-year lifespan, remains challenging. This systematic literature review (SLR) aimed to evaluate the current evidence base in AL amyloidosis.
Literature searches on clinical, health-related quality of life, economic and resource use evidence were conducted using the Embase, MEDLINE and Cochrane databases as well as gray literature.
This SLR yielded 84 unique studies from: five randomized controlled trials; 54 observational studies; 12 health-related quality of life studies, none with utility values; no economic evaluation studies; and 16 resource use studies, none with indirect costs.
This SLR highlights a paucity of published literature relating to randomized controlled trials, utility values, economic evaluations and indirect costs in AL amyloidosis.
Details
- Title: Subtitle
- Systematic literature review of evidence in amyloid light-chain amyloidosis
- Creators
- Charlene Lee - JanssenAnnette Lam - JanssenTeresa Kangappaden - EVERSANAPyper Olver - EVERSANASarah Kane - EVERSANADiana Tran - EVERSANAEric Ammann - Janssen
- Resource Type
- Journal article
- Publication Details
- Journal of comparative effectiveness research, Vol.11(6), pp.451-472
- DOI
- 10.2217/cer-2021-0261
- PMID
- 35188424
- ISSN
- 2042-6305
- eISSN
- 2042-6313
- Grant note
- name: Janssen Global Services
- Language
- English
- Date published
- 04/2022
- Academic Unit
- Epidemiology
- Record Identifier
- 9984364453302771
Metrics
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