Journal article
Systemic Lidocaine Infusion for Post-Operative Analgesia in Children Undergoing Laparoscopic Inguinal Hernia Repair: A Randomized Double-Blind Controlled Trial
Journal of clinical medicine, Vol.8(11), p.2014
11/18/2019
DOI: 10.3390/jcm8112014
PMCID: PMC6912688
PMID: 31752236
Abstract
Systemic lidocaine can provide satisfactory post-operative analgesia in adults. In this study, we assessed whether intravenous lidocaine is effective for post-operative analgesia and recovery in children undergoing laparoscopic inguinal hernia repair. A total of 66 children aged from six months to less than six years were classified in either the lidocaine (L) or control (C) groups. Children in Group L received a lidocaine infusion (a bolus dose of 1 mL kg(-1), followed by a 1.5 mg kg(-1) h(-1) infusion), whereas Group C received the same volume of 0.9% saline. The primary outcome was the number of patients who presented face, legs, activity, crying and consolability (FLACC) scores of four or more, and therefore received rescue analgesia in the post-anesthesia recovery care unit (PACU). Secondary outcomes included the highest FLACC score in the PACU, FLACC, and the parents' postoperative pain measure (PPPM) score at 48 h post-operation, as well as side effects. The number of children who received rescue analgesia in the PACU was 15 (50%) in Group L and 22 (73%) in Group C (p = 0.063). However, the highest FLACC score in PACU was lower in Group L (3.8 +/- 2.4) than in Group C (5.3 +/- 2.7) (p = 0.029). In conclusion, systemic lidocaine did not reduce the number of children who received rescue analgesia in PACU.
Details
- Title: Subtitle
- Systemic Lidocaine Infusion for Post-Operative Analgesia in Children Undergoing Laparoscopic Inguinal Hernia Repair: A Randomized Double-Blind Controlled Trial
- Creators
- Hye-Mi Lee - Yonsei UniversityKwan-Woong Choi - National Health Insurance Service Ilsan HospitalHyo-Jin Byon - Yonsei UniversityJi-Min Lee - Yonsei UniversityJeong-Rim Lee - Yonsei University
- Resource Type
- Journal article
- Publication Details
- Journal of clinical medicine, Vol.8(11), p.2014
- DOI
- 10.3390/jcm8112014
- PMID
- 31752236
- PMCID
- PMC6912688
- NLM abbreviation
- J Clin Med
- ISSN
- 2077-0383
- eISSN
- 2077-0383
- Publisher
- Mdpi
- Number of pages
- 9
- Language
- English
- Date published
- 11/18/2019
- Academic Unit
- Anesthesia
- Record Identifier
- 9984806613502771
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