Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Staphylococcus aureus

Hilmar Wisplinghoff; Harald Seifert; Marcus Coimbra; Richard P Wenzel; Michael B Edmond

doi:10.1086/322610

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Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Staphylococcus aureus

Journal article

Peer reviewed

Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Staphylococcus aureus

Hilmar Wisplinghoff, Harald Seifert, Marcus Coimbra, Richard P Wenzel and Michael B Edmond

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol.33(5), pp.733-736

09/01/2001

DOI: 10.1086/322610

PMID: 11486296

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Abstract

To determine the impact of methicillin resistance on clinical course and outcome, we evaluated nosocomial bloodstream infections (BSIs) due to Staphylococcus aureus that were diagnosed in 82 adult patients at the Medical College of Virginia Hospitals from December 1995 through May 1997. Patients with BSI due to methicillin-resistant S. aureus were compared with patients with BSI due to methicillin-susceptible S. aureus; the groups did not differ with regard to inflammatory response or outcome. Mortality was predicted by systemic inflammatory response and Acute Physiology and Chronic Health Evaluation II score but did not correlate with bacterial resistance to methicillin.

Predictive Value of Tests

Staphylococcal Infections - drug therapy

Staphylococcus aureus - isolation & purification

Systemic Inflammatory Response Syndrome - microbiology

Humans

Bacteremia - complications

Bacteremia - drug therapy

Cross Infection - mortality

Bacteremia - mortality

Logistic Models

Male

Staphylococcal Infections - complications

Cross Infection - complications

Cross Infection - drug therapy

Bacteremia - microbiology

Anti-Bacterial Agents - therapeutic use

Staphylococcal Infections - mortality

Cross Infection - microbiology

Adult

Female

Staphylococcal Infections - microbiology

Methicillin Resistance

APACHE

Cohort Studies

Details

Title: Subtitle: Systemic inflammatory response syndrome in adult patients with nosocomial bloodstream infection due to Staphylococcus aureus
Creators: Hilmar Wisplinghoff - Institute of Medical Microbiology, Immunology, and Hygiene, University of Cologne, Cologne, Germany. h.wisplinghoff@uni-koeln.de
Harald Seifert
Marcus Coimbra
Richard P Wenzel
Michael B Edmond
Resource Type: Journal article
Publication Details: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, Vol.33(5), pp.733-736
Publisher: United States
DOI: 10.1086/322610
PMID: 11486296
ISSN: 1058-4838
eISSN: 1537-6591
Language: English
Date published: 09/01/2001
Academic Unit: Internal Medicine
Record Identifier: 9983905649502771

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