T1 Glottic Carcinoma: Do Comorbidities, Facility Characteristics, and Sociodemographics Explain Survival Differences across Treatment Types?

Stephanie Misono; Schelomo Marmor; Bevan Yueh; Beth A. Virnig

doi:10.1177/0194599815572112

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T1 Glottic Carcinoma: Do Comorbidities, Facility Characteristics, and Sociodemographics Explain Survival Differences across Treatment Types?

Journal article

Peer reviewed

T1 Glottic Carcinoma: Do Comorbidities, Facility Characteristics, and Sociodemographics Explain Survival Differences across Treatment Types?

Stephanie Misono, Schelomo Marmor, Bevan Yueh and Beth A. Virnig

Otolaryngology-head and neck surgery, Vol.152(5), pp.856-862

05/01/2015

DOI: 10.1177/0194599815572112

PMCID: PMC5560894

PMID: 25715348

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https://www.ncbi.nlm.nih.gov/pmc/articles/5560894View

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Abstract

Objective Recent large-scale studies have observed differences in survival following treatment for early laryngeal carcinoma depending on treatment type but were not able to take sociodemographic, comorbidity, and facility data into account. The objective of this study was to determine whether survival differences across treatment types persist when these factors are included in the analysis. Study Design Retrospective cohort analysis. Setting Linked Surveillance, Epidemiology, and End Results (SEER)-Medicare data files. Subjects and Methods Medicare beneficiaries who were identified through the SEER registries (1991-2009) as having T1 glottic squamous cell carcinoma (scca) and a known treatment type were included. Results A total of 2338 patients with incident T1 glottic scca were identified. Most were white and male. Treatment type was radiation only in 47%, local surgery and radiation in 39%, and local surgery only in 14%. Black race and increased comorbidities were associated with worse survival. When sociodemographics, comorbidities, and facility characteristics were taken into account, survival differences were observed across treatment types, with those receiving local surgery demonstrating better overall and cancer-specific survival. Conclusion These results suggest that following treatment of T1 glottic scca, there may be survival differences across treatment types beyond those explained by sociodemographic, comorbidity, and facility characteristics.

Life Sciences & Biomedicine

Otorhinolaryngology

Science & Technology

Surgery

Details

Title: Subtitle: T1 Glottic Carcinoma: Do Comorbidities, Facility Characteristics, and Sociodemographics Explain Survival Differences across Treatment Types?
Creators: Stephanie Misono - University of Minnesota
Schelomo Marmor - University of Minnesota
Bevan Yueh - University of Minnesota
Beth A. Virnig - University of Minnesota
Resource Type: Journal article
Publication Details: Otolaryngology-head and neck surgery, Vol.152(5), pp.856-862
DOI: 10.1177/0194599815572112
PMID: 25715348
PMCID: PMC5560894
NLM abbreviation: Otolaryngol Head Neck Surg
ISSN: 0194-5998
eISSN: 1097-6817
Publisher: Sage
Number of pages: 7
Grant note: KL2TR000113 / NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS) KL2 TR000113; UL1 TR000114 / NCATS NIH HHS; United States Department of Health & Human Services; National Institutes of Health (NIH) - USA; NIH National Center for Advancing Translational Sciences (NCATS)
Language: English
Date published: 05/01/2015
Academic Unit: Otolaryngology
Record Identifier: 9984966846202771

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