T2-Weighted-Fluid-Attenuated Inversion Recovery Hyperintensity on Magnetic Resonance Imaging Is Associated With Aggressive Symptoms in Patients With Dural Arteriovenous Fistulas

Bhuvic Patel; Arindam Chatterjee; Ondra Petr; Heather Collins; Giuseppe Lanzino; Colin P Derdeyn; Gregory J Zipfel

doi:10.1161/STROKEAHA.118.024285

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T2-Weighted-Fluid-Attenuated Inversion Recovery Hyperintensity on Magnetic Resonance Imaging Is Associated With Aggressive Symptoms in Patients With Dural Arteriovenous Fistulas

Journal article

Open access

Peer reviewed

T2-Weighted-Fluid-Attenuated Inversion Recovery Hyperintensity on Magnetic Resonance Imaging Is Associated With Aggressive Symptoms in Patients With Dural Arteriovenous Fistulas

Bhuvic Patel, Arindam Chatterjee, Ondra Petr, Heather Collins, Giuseppe Lanzino, Colin P Derdeyn and Gregory J Zipfel

Stroke (1970), Vol.50(9), pp.2565-2567

09/2019

DOI: 10.1161/STROKEAHA.118.024285

PMID: 31409269

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Abstract

Background and Purpose- Several angiographic factors of dural arteriovenous fistulas (dAVFs) are associated with aggressive presentation and poor natural history. We examined the association of magnetic resonance imaging T2-weighted-Fluid-Attenuated Inversion Recovery (T2/FLAIR) hyperintensity with aggressive presentation. Methods- A cohort of dAVF patients from 2 centers was retrospectively examined. T2/FLAIR hyperintensity was determined by blinded, de-identified review and compared with angiographic grade and presenting symptoms. Results- T2/FLAIR hyperintensity was only identified in dAVF patients with cortical venous drainage (CVD). Among patients with CVD, those with T2/FLAIR hyperintensity were more likely to present with aggressive symptoms (20/23, 87.0%) than those without (6/21, 28.5%), P<0.001. All cured dAVFs with symptom resolution and available post-treatment imaging had resolution of T2/FLAIR hyperintensity. Conclusions- T2/FLAIR hyperintensity strongly correlates with aggressive presentation and CVD in dAVF patients, and may identify a subset that would benefit from early treatment.

Humans

Magnetic Resonance Imaging - adverse effects

Middle Aged

Central Nervous System Vascular Malformations - diagnostic imaging

Male

Secondary Prevention

Cerebral Angiography - methods

Young Adult

Time Factors

Adolescent

Aged, 80 and over

Adult

Female

Aged

Retrospective Studies

Central Nervous System Vascular Malformations - surgery

Cohort Studies

Details

Title: Subtitle: T2-Weighted-Fluid-Attenuated Inversion Recovery Hyperintensity on Magnetic Resonance Imaging Is Associated With Aggressive Symptoms in Patients With Dural Arteriovenous Fistulas
Creators: Bhuvic Patel - From the Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO (B.P., G.J.Z.)
Arindam Chatterjee - Department of Radiology, Medical University of South Carolina, Charleston (A.C., H.C.)
Ondra Petr - Department of Neurological Surgery, College of Medicine, Mayo Clinic, Rochester, MN (O.P., G.L.)
Heather Collins - Department of Radiology, Medical University of South Carolina, Charleston (A.C., H.C.)
Giuseppe Lanzino - Department of Neurological Surgery, College of Medicine, Mayo Clinic, Rochester, MN (O.P., G.L.)
Colin P Derdeyn - Department of Radiology, Carver College of Medicine, University of Iowa (C.P.D.)
Gregory J Zipfel - From the Department of Neurological Surgery, Washington University School of Medicine, St. Louis, MO (B.P., G.J.Z.)
Resource Type: Journal article
Publication Details: Stroke (1970), Vol.50(9), pp.2565-2567
DOI: 10.1161/STROKEAHA.118.024285
PMID: 31409269
NLM abbreviation: Stroke
ISSN: 0039-2499
eISSN: 1524-4628
Publisher: United States
Language: English
Date published: 09/2019
Academic Unit: Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
Record Identifier: 9984070883102771

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