TFIIIC boxes in the genome

Lori L Wallrath; Pamela K Geyer

doi:10.1016/j.cell.2006.05.016

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Journal article

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Peer reviewed

TFIIIC boxes in the genome

Lori L Wallrath and Pamela K Geyer

Cell (Cambridge), Vol.125(5), pp.829-831

06/02/2006

DOI: 10.1016/j.cell.2006.05.016

PMID: 16751090

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Abstract

In this issue of Cell, Noma et al. (2006) show that B-boxes and TFIIIC limit the spread of heterochromatin at the silent mat region in the fission yeast genome. Global analysis of TFIIIC distribution revealed dispersed sites of association that coalesce at the nuclear periphery, suggesting that TFIIIC may act as a barrier throughout the genome.

Schizosaccharomyces - genetics

Transcription Factors, TFIII - genetics

Schizosaccharomyces - metabolism

Heterochromatin - genetics

Cell Nucleus - genetics

DNA Polymerase III - genetics

Genome, Fungal - genetics

Gene Expression Regulation, Fungal - genetics

Binding Sites - genetics

Transcription, Genetic - genetics

DNA-Binding Proteins - genetics

Details

Title: Subtitle: TFIIIC boxes in the genome
Creators: Lori L Wallrath - Department of Biochemistry, University of Iowa, Iowa City, IA 52242, USA
Pamela K Geyer
Resource Type: Journal article
Publication Details: Cell (Cambridge), Vol.125(5), pp.829-831
Publisher: United States
DOI: 10.1016/j.cell.2006.05.016
PMID: 16751090
ISSN: 0092-8674
eISSN: 1097-4172
Language: English
Date published: 06/02/2006
Academic Unit: Obstetrics and Gynecology; Biochemistry and Molecular Biology; University College Courses
Record Identifier: 9984024555802771

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