Journal article
THE BIPHOTONIC PHOTOIONIZATION OF CHLORPROMAZINE DURING CONVENTIONAL FLASH PHOTOLYSIS: SPIN TRAPPING RESULTS WITH 5,5‐DIMETHYL‐1‐PYRROLINE‐N‐OXIDE
Photochemistry and photobiology, Vol.54(2), pp.167-173
08/1991
DOI: 10.1111/j.1751-1097.1991.tb02003.x
PMID: 1664109
Abstract
A novel combination of conventional flash photolysis and electron spin resonance (ESR) spin‐trapping has been used to demonstrate that photoionization of chlorpromazine (CPZ), and the concomitant production of hydrated electron, occurs through a stepwise biphotonic mechanism during conventional flash photolysis at wavelengths above 290 nm. The production of hydrated electron in the flash photolysis experiment has been monitored and quantified through the use of the spin trapping agent 5,5‐dimethyl‐1‐pyrroline‐A'‐oxide (DMPO). The effects of nitrous oxide, varying concentrations of CPZ and DMPO, and a range of flash intensities on the ESR spectra of the observed spin adducts of DMPO are discussed. The use of ESR spin trapping to monitor hydrated electron yields in flash photolysis experiments has the potential to permit the use of a much wider range of flash intensities than is typically possible with conventional optical experiments. Thus, there is a greater possibility of distinguishing between monophotonic and biphotonic processes.
Details
- Title: Subtitle
- THE BIPHOTONIC PHOTOIONIZATION OF CHLORPROMAZINE DURING CONVENTIONAL FLASH PHOTOLYSIS: SPIN TRAPPING RESULTS WITH 5,5‐DIMETHYL‐1‐PYRROLINE‐N‐OXIDE
- Creators
- Robert D HallGarry R BuettnerColin F Chignell
- Resource Type
- Journal article
- Publication Details
- Photochemistry and photobiology, Vol.54(2), pp.167-173
- Publisher
- Blackwell Publishing Ltd; Oxford, UK
- DOI
- 10.1111/j.1751-1097.1991.tb02003.x
- PMID
- 1664109
- ISSN
- 0031-8655
- eISSN
- 1751-1097
- Number of pages
- 7
- Language
- English
- Date published
- 08/1991
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984047610002771
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