Journal article
THE POWER OF POOP: FECAL MICROBIOTA TRANSPLANTATION FOR CLOSTRIDIUM DIFFICILE INFECTION
Transactions of the American Clinical and Climatological Association, Vol.127, pp.71-80
2016
PMCID: PMC5216499
PMID: 28066039
Abstract
The human gut is colonized with 200 to 1,000 bacterial species. Administration of antibiotics reduces the diversity of the intestinal microbiota, reduces colonization resistance, and can lead to infection with . These infections have become more prevalent and increasingly patients are experiencing multiple recurrences that are incurable with standard treatment. Although fecal microbiota transplantation (FMT) has been used for centuries in human and veterinary medicine, only recently has it be shown to be highly effective for recurrent infection. The goal of FMT is to re-introduce a complete, stable community of gut microorganisms to repair or replace the disrupted native microbiota. FMT can be delivered via nasoenteric tube, colonoscopy, or enema. Despite a cure rate approximating 90%, many barriers to FMT have limited its availability to patients. The recent development of a not-for-profit stool bank has helped to make this therapy more accessible. Additional indications for FMT are currently under investigation.
Details
- Title: Subtitle
- THE POWER OF POOP: FECAL MICROBIOTA TRANSPLANTATION FOR CLOSTRIDIUM DIFFICILE INFECTION
- Creators
- Michael B Edmond - IOWA CITY, IOWA
- Resource Type
- Journal article
- Publication Details
- Transactions of the American Clinical and Climatological Association, Vol.127, pp.71-80
- Publisher
- United States
- PMID
- 28066039
- PMCID
- PMC5216499
- ISSN
- 0065-7778
- Language
- English
- Date published
- 2016
- Academic Unit
- Infectious Diseases; Internal Medicine
- Record Identifier
- 9983905648402771
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