Journal article
Takotsubo cardiomyopathy in children
Cardiology in the young, Vol.30(11), pp.1711-1715
11/01/2020
DOI: 10.1017/S1047951120002632
PMID: 32843113
Abstract
Objective:
To explore the epidemiology and outcomes of takotsubo cardiomyopathy in children.
Methods:
A retrospective analysis of the Healthcare Cost and Utilization 2012 and 2016 Kids' Inpatient Database was performed. Patients admitted with the diagnosis of takotsubo cardiomyopathy in the age group of 1 month-20 years were identified using International Classification of Diseases (ICD)-9 code 429.83 and ICD-10 code I51.81.
Results:
Among a total of 4,860,859 discharges, there were 153 with the diagnosis of takotsubo cardiomyopathy (3.1 per 100,000 discharges). Among patients with takotsubo cardiomyopathy, 55.0% were male, 62.4% were white, and 16.7% were black. Eighty-nine percent of patients were between 12 and 20 years. Psychiatric diagnosis was documented in 46% and substance use disorder in 36.2%. Sepsis was documented in 22.8% of patients. The median length of stay was 5 days (interquartile range: 2.7-15), and median total charges were $75,080 (interquartile range: 32,176-198,336). The overall mortality for takotsubo cardiomyopathy was 7%. On multivariable regression analysis, mortality was higher in the presence of anoxic injury (odds ratio = 34.42, 95% confidence interval: 4.85-320.11, p = 0.00).
Conclusions:
Takotsubo cardiomyopathy is uncommon in children and carries a mortality rate of 7%. Most children with takotsubo cardiomyopathy are adolescent males, many of whom have psychiatric disorder or substance use disorder or both. Takotsubo cardiomyopathy should be considered in the differential diagnosis for patients who present with cardiac dysfunction and have underlying psychiatric disorders or drug abuse.
Details
- Title: Subtitle
- Takotsubo cardiomyopathy in children
- Creators
- Prithvi Sendi - Miami Children's HospitalPaul Martinez - Miami Children's HospitalMadhuradhar Chegondi - University of IowaBalagangadhar R. Totapally - Miami Children's Hospital
- Resource Type
- Journal article
- Publication Details
- Cardiology in the young, Vol.30(11), pp.1711-1715
- Publisher
- Cambridge Univ Press
- DOI
- 10.1017/S1047951120002632
- PMID
- 32843113
- ISSN
- 1047-9511
- eISSN
- 1467-1107
- Number of pages
- 5
- Language
- English
- Date published
- 11/01/2020
- Academic Unit
- Stead Family Department of Pediatrics
- Record Identifier
- 9984353928402771
Metrics
11 Record Views