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Tandem reduction–reductive alkylation of azido sugars
Journal article   Peer reviewed

Tandem reduction–reductive alkylation of azido sugars

Liqiang Chen and David F Wiemer
Tetrahedron letters, Vol.43(15), pp.2705-2708
2002
DOI: 10.1016/S0040-4039(02)00386-6

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Abstract

Catalytic hydrogenation of azido sugars has been conducted in the presence of different aldehydes to bring about a tandem reduction–reductive alkylation sequence. The reaction sequence proceeds in generally high yields, and tolerates some benzyl and benzylidene protecting groups that are sensitive to hydrogenolysis. Catalytic hydrogenation of azido sugars has been conducted in the presence of different aldehydes to bring about a tandem reduction–reductive alkylation sequence.

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