Tardive Dyskinesia versus Tardive Syndrome. What is in a name?

Karen Frei; Alicia Scott; Stanley N. Caroff; Joseph Jankovic; William Ondo; Leslie Citrome; Robert Hauser; Joseph H. Friedman; Roongroj Bhidayasiri; Martha Sajatovic; Dennis Alters; Jonathan Meyer; Stuart Factor; E.K. Tan; G. Remington; Ira Glick; Hubert Fernandez; Cynthia Comella; John Kane; Joseph McEvoy; Delwyn Miller; Clement C. Zai; J.P. Lindenmayer; Richard Trosch; Daniel D. Truong

doi:10.1016/j.parkreldis.2025.107295

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Tardive Dyskinesia versus Tardive Syndrome. What is in a name?

Journal article

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Tardive Dyskinesia versus Tardive Syndrome. What is in a name?

Karen Frei, Alicia Scott, Stanley N. Caroff, Joseph Jankovic, William Ondo, Leslie Citrome, Robert Hauser, Joseph H. Friedman, Roongroj Bhidayasiri, Martha Sajatovic, …

Parkinsonism & related disorders, Vol.133, 107295

04/2025

DOI: 10.1016/j.parkreldis.2025.107295

PMID: 39904646

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Abstract

Highlights • Five years following introduction of the first antipsychotic, tardive dyskinesia was reported. • Additional tardive syndrome phenomenologies have been identified. • Tardive syndrome symptoms worsen after DRBA discontinuation and improve with DRBA switch or dose increase. • The terms TD and tardive syndrome have been confused and more specific terminology was sought. • The term tardive syndrome was decided to be the umbrella term for the differing tardive phenomenology through an eDelphi study. • The term TD is preserved for the classic condition described with OBL stereotypy and chorea of the extremities.

Tardive syndrome

Tardive dyskinesia

Dopamine receptor blocking agents

Antipsychotics

Details

Title: Subtitle: Tardive Dyskinesia versus Tardive Syndrome. What is in a name?
Creators: Karen Frei
Alicia Scott
Stanley N. Caroff
Joseph Jankovic
William Ondo
Leslie Citrome
Robert Hauser
Joseph H. Friedman
Roongroj Bhidayasiri
Martha Sajatovic
Dennis Alters
Jonathan Meyer
Stuart Factor
E.K. Tan
G. Remington
Ira Glick
Hubert Fernandez
Cynthia Comella
John Kane
Joseph McEvoy
Delwyn Miller
Clement C. Zai
J.P. Lindenmayer
Richard Trosch
Daniel D. Truong
Resource Type: Journal article
Publication Details: Parkinsonism & related disorders, Vol.133, 107295
DOI: 10.1016/j.parkreldis.2025.107295
PMID: 39904646
NLM abbreviation: Parkinsonism Relat Disord
ISSN: 1353-8020
eISSN: 1873-5126
Publisher: ELSEVIER SCI LTD
Grant note: Christian Truong Foundation under the auspices of the International Association of Parkinsonism and Related Disorders
Funding for this research was provided by the Christian Truong Foundation under the auspices of the International Association of Parkinsonism and Related Disorders.
Language: English
Electronic publication date: 01/2025
Date published: 04/2025
Academic Unit: Psychiatry
Record Identifier: 9984775019702771

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