Journal article
Targeting the sumoylation pathway in cancer stem cells
Molecular & cellular oncology, Vol.1(3), pp.e964624-e964624
09/15/2014
DOI: 10.4161/23723548.2014.964624
PMCID: PMC4905063
PMID: 27308355
Abstract
Cancer stem cells (CSCs) represent a subset of tumor cells with tumor-initiating potential. We recently demonstrated that inhibition of the sumoylation pathway cleared the CSC population and repressed the outgrowth of basal breast cancer xenografts. Targeting the sumoylation pathway offers a novel treatment strategy for basal breast cancer.
Details
- Title: Subtitle
- Targeting the sumoylation pathway in cancer stem cells
- Creators
- Maria V Bogachek - University of IowaJames P De Andrade - University of IowaRonald J Weigel - University of Iowa
- Resource Type
- Journal article
- Publication Details
- Molecular & cellular oncology, Vol.1(3), pp.e964624-e964624
- DOI
- 10.4161/23723548.2014.964624
- PMID
- 27308355
- PMCID
- PMC4905063
- NLM abbreviation
- Mol Cell Oncol
- ISSN
- 2372-3556
- eISSN
- 2372-3556
- Publisher
- Taylor & Francis
- Language
- English
- Date published
- 09/15/2014
- Academic Unit
- Molecular Physiology and Biophysics; Anatomy and Cell Biology; Surgery; Biochemistry and Molecular Biology
- Record Identifier
- 9984284329902771
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