Journal article
Technical, angiographic and clinical outcomes of Neuroform 1, 2, 2 Treo and 3 devices in stent-assisted coiling of intracranial aneurysms
Journal of neurointerventional surgery, Vol.4(5), pp.368-374
09/2012
DOI: 10.1136/neurintsurg-2011-010076
PMID: 21990523
Abstract
Background and purpose Since 2002 the Neuroform stent has expanded endovascular treatment of wide-necked intracranial aneurysms. A study was undertaken to assess the technical success rates and angiographic and clinical outcomes in stent-assisted coiling with Neuroform 1, 2, 2 Treo and 3. Methods Patients undergoing Neuroform stent-assisted coiling were enrolled in a prospective registry that included 156 stent deployment attempts in 113 consecutive patients (mean age 53, range 25–78). Deployment success and difficulty, stent movement, procedural complications, immediate/delayed aneurysm occlusion and in-stent stenosis on angiographic follow-up were compared among Neuroform 1, 2, 2 Treo and 3 stents using a log likelihood ratio χ2 test. Results Of 156 stent attempts, 123 (79%) were deployed (Neuroform 1: 8/9 (89%), Neuroform 2: 50/66 (76%), Neuroform 2 Treo: 9/11 (82%), Neuroform 3: 56/70 (80%)) with a symptomatic complication rate of 1.9% (3/156; 2 transient ischemic attacks, 1 stroke, no deaths). Non-target stent placement (1/8 (13%), 6/50 (12%), 2/9 (22%), 3/56 (5%)), difficult placement (2/8 (25%), 10/50 (20%), 5/9 (56%), 6/56 (11%)), stent movement (1/8 (13%), 4/50 (8%), 0/9 (0%), 4/56 (7%)), procedural complications (1/9 (11%), 7/66 (11%), 2/11 (18%), 2/70 (3%)) and immediate near complete aneurysm occlusion (6/6 (100%), 24/37 (65%), 5/7 (71%), 40/45 (89%)) trended towards improvement with each generation. Improvements in difficult stent placement and immediate aneurysm occlusion were significant (p=0.01 and 0.03, respectively). Conclusion Neuroform stent-assisted coiling has evolved through four generations as a safe and effective means of treating wide-necked intracranial aneurysms.
Details
- Title: Subtitle
- Technical, angiographic and clinical outcomes of Neuroform 1, 2, 2 Treo and 3 devices in stent-assisted coiling of intracranial aneurysms
- Creators
- Yasha Kadkhodayan - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USAChristopher T Somogyi - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USADeWitte T Cross - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USAColin P Derdeyn - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USAGregory J Zipfel - Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USAMichael R Chicoine - Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USAKeith M Rich - Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USARobert L Grubb - Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USARalph G Dacey - Department of Neurological Surgery, Washington University School of Medicine, St Louis, Missouri, USAChristopher J Moran - Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri, USA
- Resource Type
- Journal article
- Publication Details
- Journal of neurointerventional surgery, Vol.4(5), pp.368-374
- DOI
- 10.1136/neurintsurg-2011-010076
- PMID
- 21990523
- ISSN
- 1759-8478
- eISSN
- 1759-8486
- Language
- English
- Date published
- 09/2012
- Academic Unit
- Neurology; Radiology; Iowa Neuroscience Institute; Neurosurgery
- Record Identifier
- 9984020601702771
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