Journal article
Technical considerations in adult lung transplantation
Seminars in thoracic and cardiovascular surgery, Vol.16(4), pp.322-332
2004
DOI: 10.1053/j.semtcvs.2004.09.013
PMID: 15635536
Abstract
Over the last two decades, lung transplantation has evolved from experimental to a definite therapy for a variety of end stage lung disorders. This can be attributed to the development of better immunosuppression, better graft preservation, and refinement in the operative techniques. Techniques have been developed to accommodate anomalous donor anatomy, suboptimal harvests, and to increase the donor pool. Recipient pneumonectomy and allograft implantation techniques have evolved to minimize periopertive morbidity and mortality. However, a numver of major problems await solution; for example, inadequate donor supply, ischemia-reperfusion injury, and chronic allograft rejection. Novel therapies are being investigated based on experimental studies; however, multiinstitution trials will be required to determine the clinical impact of these strategies. © 2004 Elsevier Inc. All rights reserved.
Details
- Title: Subtitle
- Technical considerations in adult lung transplantation
- Creators
- Kalpaj Parekh - Washington University in St. LouisG Alexander Patterson - Washington University in St. Louis
- Resource Type
- Journal article
- Publication Details
- Seminars in thoracic and cardiovascular surgery, Vol.16(4), pp.322-332
- DOI
- 10.1053/j.semtcvs.2004.09.013
- PMID
- 15635536
- ISSN
- 1043-0679
- eISSN
- 1532-9488
- Language
- English
- Date published
- 2004
- Academic Unit
- Anatomy and Cell Biology; Cardiothoracic Surgery
- Record Identifier
- 9984284343902771
Metrics
9 Record Views