Journal article
Technological advances in ventricular tachycardia catheter ablation: the relentless quest for novel solutions to old problems
Journal of interventional cardiac electrophysiology, Vol.67(4), pp.855-864
06/01/2024
DOI: 10.1007/s10840-023-01705-7
PMID: 38087147
Abstract
Several novel technologies allowing catheter ablation (CA) with a favorable safety/efficacy profile have been recently developed, but not yet extensively clinically tested in the setting of ventricular tachycardia CA.
In this technical report, we overview technical aspects and preclinical/clinical information concerning the application of three novel CA technologies in the ventricular milieu: a pulsed field ablation (PFA) generator (CENTAURI™, Galaxy Medical) to be used with linear, contact force-sensing radiofrequency ablation catheters; a contact force-sensing radiofrequency ablation catheter equipped with six thermocouples and three microelectrodes (QDOT Micro™, Biosense-Webster), allowing high-resolution mapping and temperature-controlled CA; and a flexible and mesh-shaped irrigation tip, contact force-sensing radiofrequency ablation catheter (Tactiflex, Abbott). We also report three challenging VT cases in which CA was performed using these technologies.
The CENTAURI system was used with the Tacticath™ (Abbott) ablation catheter to perform ventricular PFA in a patient with advanced heart failure, electrical storm, and a deep intramural septal substrate. Microelectrode mapping using QDOT Micro™ helped to refine substrate assessment in a VT patient with congenitally corrected transposition of the great arteries, and allowed the identification of the critical components of the VT circuit, which were successfully ablated. Tactiflex™ was used in two challenging CA cases (one endocardial and one epicardial), allowing acute and mid-term control of VT episodes without adverse events.
The ideation and development of novel technologies initially intended to treat atrial arrhythmias and successfully implemented in the ventricular milieu is contributing to the progressive improvement in the clinical benefits derived from VT CA, making this procedure key for successful management of increasingly complex patients.
Details
- Title: Subtitle
- Technological advances in ventricular tachycardia catheter ablation: the relentless quest for novel solutions to old problems
- Creators
- Paolo Compagnucci - Marche Polytechnic UniversityYari Valeri - Marche Polytechnic UniversitySergio Conti - Department of Cardiology, Electrophysiology Unit, ARNAS Civico - Di Cristina - Benfratelli, Palermo, ItalyGiovanni Volpato - Marche Polytechnic UniversityLaura Cipolletta - Marche Polytechnic UniversityQuintino Parisi - Marche Polytechnic UniversityLeonardo D'Angelo - Marche Polytechnic UniversityFrancesca Campanelli - Marche Polytechnic UniversityLaura Carboni - Cardiac Surgery Anesthesia and Critical Care Unit, University Hospital "Ospedali Riuniti,", Ancona, ItalyGiuseppe Sgarito - Department of Cardiology, Electrophysiology Unit, ARNAS Civico - Di Cristina - Benfratelli, Palermo, ItalyAndrea Natale - Scripps ClinicMichela Casella - Marche Polytechnic UniversityAntonio Dello Russo - Marche Polytechnic University
- Resource Type
- Journal article
- Publication Details
- Journal of interventional cardiac electrophysiology, Vol.67(4), pp.855-864
- DOI
- 10.1007/s10840-023-01705-7
- PMID
- 38087147
- NLM abbreviation
- J Interv Card Electrophysiol
- ISSN
- 1572-8595
- eISSN
- 1572-8595
- Language
- English
- Date published
- 06/01/2024
- Academic Unit
- Internal Medicine
- Record Identifier
- 9984822988502771
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