Journal article
Temporal Trends of High‐Intensity Statin Therapy Among Veterans Treated With Percutaneous Coronary Intervention
Journal of the American Heart Association, Vol.7(5), e007370
03/04/2018
DOI: 10.1161/JAHA.117.007370
PMCID: PMC5866316
PMID: 29503265
Abstract
Background
The 2013 American College of Cardiology/American Heart Association blood cholesterol guideline recommends high‐intensity statin therapy among certain groups of patients, but full implementation of the guideline has not yet been satisfactory. We aimed to investigate the temporal trends and predictors of high‐intensity statin therapy among veterans who had been treated with percutaneous coronary intervention (PCI) and followed up by cardiologists within the Veterans Health Administrative system.
Methods and Results
A retrospective cohort study was conducted at the Veterans Health Administrative system including all patients >18 years old who had their PCI procedure between October 2010 and September 2016. National Veterans Health Administrative databases were used to retrieve study participant's demographics, comorbid conditions, statin type and dose within 90 days before and after the PCI procedure. There were 48 862 patients who underwent a PCI procedure during the study period. High‐intensity statin use at 90 days post‐PCI rose from 23% in 2010 to 37% before release of the 2013 American College of Cardiology/American Heart Association cholesterol guideline, then rose sharply to 80% by 2016. The projected 10‐year risk of arteriosclerotic cardiovascular disease events among our study population was projected to be ≈1841 fewer if the cohort had received high‐intensity statin therapy versus moderate‐intensity statin.
Conclusions
By 2016, the 2013 American College of Cardiology/American Heart Association blood cholesterol guideline was well implemented among veterans who had a PCI procedure in the Veterans Health Administrative system, suggesting systems of care can be improved to increase rates of high‐intensity statin initiation.
Details
- Title: Subtitle
- Temporal Trends of High‐Intensity Statin Therapy Among Veterans Treated With Percutaneous Coronary Intervention
- Creators
- Aref A Bin Abdulhak - University of IowaMary Vaughan-Sarrazin - University of Iowa Carver College of MedicinePeter Kaboli - University of Iowa, EpidemiologyPhillip A Horwitz - University of Iowa, Internal MedicineHilary Mosher - University of Iowa, Internal MedicineGardar Sigurdsson - University of Iowa Carver College of MedicineNicholas E Walker - University of Iowa, Internal MedicineRobert Wallace - University of Iowa, Internal MedicineJennifer G Robinson - University of Iowa, Epidemiology
- Resource Type
- Journal article
- Publication Details
- Journal of the American Heart Association, Vol.7(5), e007370
- DOI
- 10.1161/JAHA.117.007370
- PMID
- 29503265
- PMCID
- PMC5866316
- NLM abbreviation
- J Am Heart Assoc
- ISSN
- 2047-9980
- eISSN
- 2047-9980
- Publisher
- Oxford: Wiley-Blackwell
- Number of pages
- 7
- Copyright
- © 2018 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
- Grant note
- Veterans Health Administration Health Services Research and Development Department of Veterans Affairs Office of Research and Development
- Language
- English
- Date published
- 03/04/2018
- Academic Unit
- Health Management and Policy; Heart and Vascular Center; Injury Prevention Research Center; Internal Medicine
- Record Identifier
- 9983761183702771
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