Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract

Ebbing Lautenbach; Anthony D Harris; Eli N Perencevich; Irving Nachamkin; Pam Tolomeo; Joshua P Metlay

doi:10.1128/AAC.49.2.798-800.2005

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Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract

Journal article

Open access

Peer reviewed

Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract

Ebbing Lautenbach, Anthony D Harris, Eli N Perencevich, Irving Nachamkin, Pam Tolomeo and Joshua P Metlay

Antimicrobial agents and chemotherapy, Vol.49(2), pp.798-800

02/2005

DOI: 10.1128/AAC.49.2.798-800.2005

PMCID: PMC547369

PMID: 15673772

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Abstract

Among 63 patients enrolled in a prospective cohort study of gut colonization with fluoroquinolone-resistant Escherichia coli, the sensitivity of perirectal swab compared to stool sample was 90% (95% confidence interval [CI], 70 to 99%) and the specificity was 100% (95% CI, 91 to 100%). For rectal swab, the sensitivity was 90% (95% CI, 68 to 99%) and the specificity was 100% (95% CI, 91 to 100%).

Rectum - microbiology

Reproducibility of Results

Cross-Sectional Studies

Escherichia coli - drug effects

Humans

Middle Aged

Drug Resistance, Bacterial

Male

Microbial Sensitivity Tests

Feces - microbiology

Fluoroquinolones - pharmacology

Aged, 80 and over

Adult

Female

Aged

Anti-Bacterial Agents - pharmacology

Digestive System - microbiology

Cohort Studies

Details

Title: Subtitle: Test characteristics of perirectal and rectal swab compared to stool sample for detection of fluoroquinolone-resistant Escherichia coli in the gastrointestinal tract
Creators: Ebbing Lautenbach - Division of Infectious Diseases, Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6021, USA. elautenb@cceb.med.upenn.edu
Anthony D Harris
Eli N Perencevich
Irving Nachamkin
Pam Tolomeo
Joshua P Metlay
Resource Type: Journal article
Publication Details: Antimicrobial agents and chemotherapy, Vol.49(2), pp.798-800
Publisher: United States
DOI: 10.1128/AAC.49.2.798-800.2005
PMID: 15673772
PMCID: PMC547369
ISSN: 0066-4804
eISSN: 1098-6596
Grant note: U18-HS10399 / AHRQ HHS RS1/CCR320627-01 / DRS NIH HHS U18 HS010399 / AHRQ HHS
Language: English
Date published: 02/2005
Academic Unit: Epidemiology; Internal Medicine
Record Identifier: 9983779296302771

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