Testing Life Course Models Whereby Juvenile and Adult Adversity Combine to Influence Speed of Biological Aging

Ronald L Simons; Man-Kit Lei; Steven R H Beach; Leslie Gordon Simons; Ashley B Barr; Frederick X Gibbons; Robert A Philibert

doi:10.1177/0022146519859896

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Testing Life Course Models Whereby Juvenile and Adult Adversity Combine to Influence Speed of Biological Aging

Journal article

Peer reviewed

Testing Life Course Models Whereby Juvenile and Adult Adversity Combine to Influence Speed of Biological Aging

Ronald L Simons, Man-Kit Lei, Steven R H Beach, Leslie Gordon Simons, Ashley B Barr, Frederick X Gibbons and Robert A Philibert

Journal of health and social behavior, Vol.60(3), pp.291-308

09/2019

DOI: 10.1177/0022146519859896

PMCID: PMC7751897

PMID: 31409156

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https://www.ncbi.nlm.nih.gov/pmc/articles/7751897View

Open Access

Abstract

The present study extends prior research on the links between social adversity and aging by employing more comprehensive measures of adversity and a new gene expression index of aging. Hierarchical regression and 20 years of data from a sample of 381 black Americans were used to test models regarding the impact of social adversity on speed of aging. Consistent with the early life sensitivity model, early adversity continued to predict accelerated aging after controlling for adult adversity. Contrary to the pathway model, adult adversity was not related to aging following controls for early adversity. The cumulative stress model received partial support as high adversity during adulthood amplified the effect of early adversity on aging. Finally, consonant with the social change model, low adversity during adulthood buffered the effect of early adversity on aging. These findings held after controlling for health behaviors such as smoking, diet, and exercise.

African Americans

Georgia

Health Status Disparities

Humans

Aging - psychology

Male

Aging - blood

Regression Analysis

Iowa

Aging - physiology

Adolescent

Stress, Psychological

Adult

Female

Resilience, Psychological

Databases, Factual

Details

Title: Subtitle: Testing Life Course Models Whereby Juvenile and Adult Adversity Combine to Influence Speed of Biological Aging
Creators: Ronald L Simons - University of Georgia, Athens, GA, USA
Man-Kit Lei - University of Georgia, Athens, GA, USA
Steven R H Beach - University of Georgia, Athens, GA, USA
Leslie Gordon Simons - University of Georgia, Athens, GA, USA
Ashley B Barr - SUNY Buffalo, Buffalo, NY, USA
Frederick X Gibbons - University of Connecticut, Storrs, CT, USA
Robert A Philibert - University of Iowa, Psychiatry
Resource Type: Journal article
Publication Details: Journal of health and social behavior, Vol.60(3), pp.291-308
DOI: 10.1177/0022146519859896
PMID: 31409156
PMCID: PMC7751897
NLM abbreviation: J Health Soc Behav
ISSN: 0022-1465
eISSN: 2150-6000
Publisher: United States
Grant note: R21 DA034457 / NIDA NIH HHS R01 MH062668 / NIMH NIH HHS R01 DA021898 / NIDA NIH HHS R01 HL118045 / NHLBI NIH HHS R01 MH062666 / NIMH NIH HHS R01 AG055393 / NIA NIH HHS R01 HD080749 / NICHD NIH HHS R01 DA018871 / NIDA NIH HHS
Language: English
Date published: 09/2019
Academic Unit: Roy J. Carver Department of Biomedical Engineering; Psychiatry; Iowa Neuroscience Institute
Record Identifier: 9984070400802771

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