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Testing for Dose-Response Relationships in Health Messaging: Dosage, Framing, and Intentions to Exercise
Journal article   Peer reviewed

Testing for Dose-Response Relationships in Health Messaging: Dosage, Framing, and Intentions to Exercise

Helen M Lillie, Alexis S Vega, Yi Liao, Dallin R Adams and Jakob D Jensen
Journal of health communication
05/14/2026
DOI: 10.1080/10810730.2026.2673055
PMID: 42135955

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Abstract

Determining the ideal dosage to maximize benefits and minimize side effects is a vital component of treatment. Yet, dosage has received limited attention in health communication. Existing scholarship suggests that gain and loss frames may require different dosage levels. The current research tested this supposition in a 3 (dose amount: 1, 2, or 3) × 2 (message frame: gain/loss) message experiment (  = 1007), operationalizing a dose as two bullet points detailing the benefits of exercise. The three-dose message yielded greater exercise intentions compared to the two-dose message. A gain-framed, three-dose message generated the highest perceived benefits of exercise. Dose had a positive, indirect effect on exercise intentions via greater perceived benefits and greater perceived dose. These findings underscore the pressing need to further theorize dosage in health communication scholarship.
Exercise reactance perceived dose Dosage gain framing

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