Journal article
The Application of Current Proposed Venous Thromboembolism Risk Assessment Model for Ambulatory Patients With Cancer
Clinical and applied thrombosis/hemostasis, Vol.24(3), pp.429-433
04/01/2018
DOI: 10.1177/1076029617692880
PMCID: PMC6714656
PMID: 28183196
Abstract
Venous thromboembolism (VTE) is a commonly encountered problem in patients with cancer. In recent years, cancer treatment paradigm has shifted with most therapy offered in ambulatory outpatient settings. Excess of half VTEs in patients with cancer occur in outpatient settings without prior hospitalization, where current practice guidelines do not recommend routine prophylaxis. Risk assessment models (RAMs) for VTE in such patients were recently introduced. This study aims to assess the practical application of one of these models in clinical practice. Medical records and hospital electronic database were searched for patients with cancer having VTE. Known risk factors were collected, and risk assessment was done using the Khorana RAM. Over a 10-year period, 346 patients developed VTE in ambulatory settings. Median age was 57 and 59.0% were females. Lower extremities were involved in 196 (56.6%), while 96 (27.7%) had pulmonary embolism. Most (76.6%) patients had stage IV disease, only 9.0% had stage I or II disease. Only 156 (45.1%) patients were on active chemotherapy, for whom Khorana risk assessment score was calculated. In these patients, high risk was identified in 31 (19.9%) patients, while 81 (51.9%) had intermediate risk and 44 (28.2%) had low risk. No patients were on prophylaxis prior to VTE. Most ambulatory patients with cancer who developed VTE were not on chemotherapy, and many of those who were on active treatment had low Khorana risk scores. This illustrates the need to modify the model or develop a new one that takes into consideration this group of patients.
Details
- Title: Subtitle
- The Application of Current Proposed Venous Thromboembolism Risk Assessment Model for Ambulatory Patients With Cancer
- Creators
- Hikmat Abdel-Razeq - King Hussein Cancer CenterAsem Mansour - King Hussein Cancer CenterSalwa S. Saadeh - King Hussein Cancer CenterMahmoud Abu-Nasser - King Hussein Canc Ctr, Dept Internal Med, Queen Rania Al Abdullah St, Amman 11914, JordanMohammad Makoseh - King Hussein Canc Ctr, Dept Internal Med, Queen Rania Al Abdullah St, Amman 11914, JordanMurad Salam - King Hussein Cancer CenterAlaa Abufara - King Hussein Cancer CenterYousef Ismael - King Hussein Cancer CenterAlaa Ibrahim - King Hussein Cancer CenterGhaleb Khirfan - King Hussein Cancer CenterMohammad Ibrahim - King Hussein Cancer Center
- Resource Type
- Journal article
- Publication Details
- Clinical and applied thrombosis/hemostasis, Vol.24(3), pp.429-433
- Publisher
- Sage
- DOI
- 10.1177/1076029617692880
- PMID
- 28183196
- PMCID
- PMC6714656
- ISSN
- 1076-0296
- eISSN
- 1938-2723
- Number of pages
- 5
- Language
- English
- Date published
- 04/01/2018
- Academic Unit
- Radiation Oncology
- Record Identifier
- 9984313090302771
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