Journal article
The CEPH consortium linkage map of human chromosome 2
Genomics (San Diego, Calif.), Vol.14(4), pp.1055-1063
1992
DOI: 10.1016/S0888-7543(05)80129-6
PMID: 1478647
Abstract
This paper describes the Centre d'Etude du Polymorphisme Humain (CEPH) consortium linkage map of chromosome 2. The map contains 36 loci defined by genotyping generated from the CEPH family DNAs. A total of 73 different markers were typed by 14 contributing laboratories; of these, 36 loci are ordered on the map with likelihood support of at least 1000:1. Markers are placed along the length of the chromosome but no markers were available to anchor the map at either telomere or the centromere. Multilocus linkage analysis has produced male, female, and sex-averaged maps extending for 261, 430, and 328 cM, respectively. The sex-averaged map contains five intervals greater than 15 cM and the mean genetic distance between the 36 uniquely placed loci is 9.1 cM.
Details
- Title: Subtitle
- The CEPH consortium linkage map of human chromosome 2
- Creators
- Nigel K Spurr - Human Genetic Resources Unit, Imperial Cancer Research Fund, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3LD, EnglandSimon Cox - Human Genetic Resources Unit, Imperial Cancer Research Fund, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3LD, EnglandStephen P Bryant - Human Genetic Resources Unit, Imperial Cancer Research Fund, Blanche Lane, South Mimms, Potters Bar, Herts EN6 3LD, EnglandJohn Attwood - MRC Human Biochemical Genetics Unit, The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, EnglandElizabeth B Robson - Department of Genetics and Biometry, The Galton Laboratory, University College London, Wolfson House, 4 Stephenson Way, London NW1 2HE, EnglandDenis C Shields - CRC Genetic Epidemiology Research Group, Department of Child Health, Level G, Princess Anne Hospital, Southampton SO9 4HA, EnglandTodd Steinbrueck - Genetics Department, Washington University School of Medicine, Box 8232, 660 South Euclid Ave, St Louis, Missouri 63110, USATrefor Jenkins - MRC Human Ecogenetics Research Unit, Department of Human Genetics, School of Pathology, The South African Institute for Medical Research and University of the Witwatersrand, Johannesburg, South AfricaJeffrey C Murray - Department of Pediatrics, University of Iowa, Iowa City, Iowa 52242, USAKenneth K Kidd - Department of Human Genetics, Yale University School of Medicine, I-310 SHM, P.O. Box 3333, New Haven, Connecticut 06510-8005, USAMarshall L Summar - Department of Pediatrics, Vanderbilt University Medical Center, T 2402, Medical Center, North Nashville, Tennessee 37232, USAPetros Tsipouras - Molecular Genetics Laboratory, Department of Pediatrics, University of Connecticut, Health Center, Farmington, Connecticut 06032, USAAndries E Retief - University of Stellenbosch, J. S. Marais Building, Victoria Street, 7600 Stellenbosch, South AfricaTorben A Kruse - Institute for Human Genetik, Bartholin Bygningen, Aarhus Universitet, DK-8000 Aarhus C, DenmarkAllen E Bale - Department of Human Genetics, Yale University School of Medicine, I-310 SHM, P.O. Box 3333, New Haven, Connecticut 06510-8005, USAGilles Vergnaud - Centre d'etudes du Bouchet, BP No. 3, 91710 Vert Le Petit, FranceJames L Weber - Marshfield Medical Research Foundation, 1000 North Oak Avenue, Marshfield, Wisconsin 54449, USAO.W McBride - Laboratory of Biochemistry, National Cancer Institute, Building 37, National Institutes of Health, Bethesda, Maryland 20892, USAHelen Donis-Keller - Genetics Department, Washington University School of Medicine, Box 8232, 660 South Euclid Ave, St Louis, Missouri 63110, USARaymond L White - Howard Hughes Medical Institute, University of Utah, 600 Wintrobe Building, Salt Lake City, Utah 84132, USA
- Resource Type
- Journal article
- Publication Details
- Genomics (San Diego, Calif.), Vol.14(4), pp.1055-1063
- DOI
- 10.1016/S0888-7543(05)80129-6
- PMID
- 1478647
- NLM abbreviation
- Genomics
- ISSN
- 0888-7543
- eISSN
- 1089-8646
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1992
- Academic Unit
- Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984025595702771
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