Journal article
The CEPH consortium primary linkage map of human chromosome 10
Genomics (San Diego, Calif.), Vol.6(3), pp.393-412
1990
DOI: 10.1016/0888-7543(90)90469-B
PMID: 1970325
Abstract
The first CEPH consortium map, that of chromosome 10, is presented. This primary linkage map contains 28 continuously linked loci defined by genotypes generated from CEPH family DNAs with 37 probe and enzyme combinations. Cytogenetic localization of some of the genetic markers indicates that the consortium map extends, at least, from 10p13 to 10q26. The order of loci on the consortium map agrees with the physical localization data. The female map spans 309 cM (206 cM if an approximation of interference is included in the mapping function used to construct the map), and the mean genetic distance of intervals in 11 cM (7 cM). Also presented are maps of chromosome 10 from each of five CEPH collaborating laboratories, based on genotypes for all relevant markers in the CEPH data-base. The CEPH consortium map of chromosome 10 should be useful for localization of any gene of interest falling within the span covered. The genotypes in the chromosome 10 consortium map database are now available to the scientific community.
Details
- Title: Subtitle
- The CEPH consortium primary linkage map of human chromosome 10
- Creators
- Raymond L White - Howard Hughes Medical Institute, University of Utah Medical Center, Salt Lake City, Utah, USAJean-Marc Lalouel - Howard Hughes Medical Institute, University of Utah Medical Center, Salt Lake City, Utah, USAYusuke Nakamura - Howard Hughes Medical Institute, University of Utah Medical Center, Salt Lake City, Utah, USAHelen Donis-Keller - Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110 USAPhilip Green - Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63110 USADonald W Bowden - Collaborative Research, Inc., Bedford, Massachusetts 01730 USAChristopher G.P Mathew - Institute of Cancer Research, Sutton, Surrey SM2 5NG, EnglandDouglas F Easton - Institute of Cancer Research, Sutton, Surrey SM2 5NG, EnglandElizabeth B Robson - The Galton Laboratory, University College London, London NW1 2HE, EnglandNewton E Morton - Department of Community Medicine, University of Southampton, Southampton S09 4XY, EnglandJames F Gusella - Neurogenetics Laboratory, Massachusetts General Hospital, Boston, Massachusetts 02114 USAJonathan L Haines - Neurogenetics Laboratory, Massachusetts General Hospital, Boston, Massachusetts 02114 USAAndries E Retief - Department of Human Genetics, Faculty of Medicine, University of Stellenbosch, Tygerberg, 7505 South AfricaKenneth K Kidd - Department of Human Genetics, Yale University School of Medicine, New Haven, Connecticut 06510-8005 USAJeffrey C Murray - Department of Pediatrics, Division of Medical Genetics, College of Medicine, University of Iowa, Iowa City, Iowa 52242 USAG.Mark Lathrop - Centre d'Etude du Polymorphisme Humain (CEPH), 75010 Paris, FranceHoward M Cann - Centre d'Etude du Polymorphisme Humain (CEPH), 75010 Paris, France
- Resource Type
- Journal article
- Publication Details
- Genomics (San Diego, Calif.), Vol.6(3), pp.393-412
- DOI
- 10.1016/0888-7543(90)90469-B
- PMID
- 1970325
- NLM abbreviation
- Genomics
- ISSN
- 0888-7543
- eISSN
- 1089-8646
- Publisher
- Elsevier Inc
- Language
- English
- Date published
- 1990
- Academic Unit
- Anatomy and Cell Biology; Stead Family Department of Pediatrics; Epidemiology; Pediatric Dentistry; Craniofacial Anomalies Research Center; Dental Research
- Record Identifier
- 9984025331502771
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